1,3-Dichloroisoquinoline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 7742-73-6 |
| Product name | 1,3-Dichloroisoquinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1,3-Dichloroisoquinoline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1,3-Dichloroisoquinoline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1,3-Dichloroisoquinoline
| Industry | Application | Process |
|---|---|---|
| Pesticides | Fungicide intermediate | Used in the synthesis of novel triazole fungicides (e.g., epoxiconazole) via nucleophilic substitution or coupling reactions to introduce the isoquinoline heterocyclic structure |
| Pharmaceuticals | Pharmaceutical intermediate | Serves as a key intermediate for constructing nitrogen-containing heterocyclic scaffolds; employed in synthesizing antitumor and antiviral active molecules, typically in Pd-catalyzed cross-coupling or amination reactions |
| Dyes & Pigments | Organic pigment intermediate | Applied in the synthesis of high-performance isoquinoline-based fluorescent dyes; color lake pigments are prepared through multi-step reactions including nitration, reduction, diazotization, and coupling |
Manufacturing Quality Control of 1,3-Dichloroisoquinoline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard under validated chromatographic conditions. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of structurally related impurities using reversed-phase C18 column and UV absorbance at 254 nm. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling and FID detector | Headspace GC analysis to detect and quantify volatile organic solvents (e.g., dichloromethane, toluene) according to ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Chloride Content | Potentiometric Titration with Silver Nitrate | Titration with standardized AgNO3 solution; endpoint detected by silver ion-selective electrode responding to free chloride ions. |
| Heavy Metals | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and dilution. |
| Acid-Value | Acid-Base Titration with NaOH standard solution | Neutralization of acidic impurities (e.g., HCl, carboxylic acids) using phenolphthalein indicator or potentiometric endpoint. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary tube apparatus per USP <741>. |
| Appearance | Visual Inspection in Standardized Glass Container | Assessment of physical state, color, and clarity against white/black background under controlled lighting per EP 2.2.1. |
| Particle Size Distribution | Laser Diffraction Particle Size Analyzer | Measurement of particle size distribution in dry or dispersed state using Mie scattering theory and optical detection. |
| Bulk Density | Tap Density Tester (ASTM D1895) | Determination of mass per unit volume after controlled tapping of a known mass of sample in a graduated cylinder. |
| Organic Volatile Impurities (OVI) | Gas Chromatography-Mass Spectrometry (GC-MS) | Identification and quantification of non-specified volatile organic impurities using retention time and mass spectral matching. |
Technical Specifications of 1,3-Dichloroisoquinoline
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 78–82°C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1,3-Dichloroisoquinoline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1,3-Dichloroisoquinoline
Packaging of 1,3-Dichloroisoquinoline
Industrial 1,3-Dichloroisoquinoline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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