Ethyl indole-3-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 776-41-0 |
| Product name | Ethyl indole-3-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl indole-3-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl indole-3-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl indole-3-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of drug intermediates for anticancer, anti-inflammatory, and neuroactive compounds | Prepared via N-alkylation or C-3 esterification of indole with ethoxycarbonylating reagents (e.g., diethyl carbonate) under basic conditions |
| Pesticides | Intermediate for indole-containing pesticides, including plant growth regulators and insecticides | Electrophilic substitution of indole with ethyl chloroacetate or ethoxycarbonyl halides in the presence of a catalyst |
| Chemical Synthesis | Building block for indole alkaloids and precursors to functional materials | Derived via Fischer indole synthesis or prepared in two steps from indole-3-carbaldehyde via oxidation followed by esterification |
Manufacturing Quality Control of Ethyl indole-3-carboxylate
| Test Item | Common Test Method | Method Summary |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible foreign matter under natural light or standard illumination. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically at 254 nm or 280 nm). Identify components by retention time and quantify purity using peak area normalization or external standard method. |
| Assay | HPLC External Standard Method or UV Spectrophotometry | Construct a calibration curve using standard solutions of known concentrations; calculate the actual content based on sample peak area or absorbance. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H-NMR and ¹³C-NMR are used to confirm molecular structure by comparing characteristic peak positions with literature data. |
| Structural Confirmation | Mass Spectrometry (MS) | Determine the molecular ion peak ([M]+ or [M+H]+) using EI-MS or ESI-MS to verify that the molecular weight matches the target compound. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from manufacturing (e.g., ethanol, toluene) according to ICH guidelines, using an FID detector. |
| Moisture Content | Karl Fischer Titration | Accurately determine water content in samples using electrochemical titration; suitable for trace moisture analysis. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range using capillary method or automatic melting point apparatus, and compare with literature values (approximately 68–70°C) to assess purity. |
| Related Substances (Impurities) | HPLC Method | Separate the main peak from impurity peaks using gradient elution, detect and quantify individual impurities, and evaluate whether the impurity profile meets quality specifications. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detect residual heavy metals such as lead, cadmium, and mercury to ensure compliance with pharmacopoeial or safety limit requirements. |
Technical Specifications of Ethyl indole-3-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | Light yellow to brown crystalline powder |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Conforms to reference standard |
| Identification (IR) | Conforms to reference standard |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl indole-3-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl indole-3-carboxylate
Packaging of Ethyl indole-3-carboxylate
Industrial Ethyl indole-3-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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