China Factory Direct
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| CAS number | 784-38-3 |
| Product name | 2-Amino-5-chloro-2'-fluorobenzophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antidepressant drugs | Introduces key functional groups via acylation |
| Pesticides | Preparation of fluorinated insecticide intermediates | Aromatic nucleophilic substitution |
| Dyes | Synthesis of specific dye intermediates | Coupling combined with reduction |
| Materials Chemistry | Synthesis of photosensitive resins | Photoinitiated polymerization |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identity | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance (¹H NMR) |
Confirm the compound structure as 2-amino-5-chloro-2'-fluoro diphenyl ketone by comparing characteristic absorption peaks in IR spectra, HPLC retention time with reference standards, or ¹H NMR chemical shifts and coupling constants. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol-water or acetonitrile-buffered salt as mobile phase, UV detector (usually at 254 nm) for detection. Calculate the content of the main component using external standard method to ensure compliance with pharmacopoeia or enterprise standards (e.g., ≥98.0%). |
| Related Substances | High-Performance Liquid Chromatography (HPLC) | Separate the main peak from potential impurities (such as starting materials, intermediates, by-products, degradation products) using gradient elution. Control the limits of individual impurities (typically ≤0.5%) and total impurities (typically ≤1.0%) using area normalization or main component self-reference method with correction factors. |
| Residual Solvents | Gas Chromatography (GC), Headspace Sampling (HS-GC) | Determine residual organic solvents (such as toluene, dichloromethane, ethanol, etc.) potentially left from the synthetic process using headspace gas chromatography with FID detector. Quantify according to ICH Q3C guidelines. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Pressure Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, measure the mass loss to assess moisture and volatile matter content, typically required to be ≤0.5%. |
| Sulfated Ash | High-Temperature Incineration Method | Charcoal the sample and incinerate it in a high-temperature furnace (700–800°C), add sulfuric acid, and weigh the residue. This is used to control the total amount of inorganic impurities, typically required to be ≤0.1%. |
| Heavy Metals | Atomic Absorption Spectrometry (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Determine the content of heavy metals such as lead, cadmium, mercury, and arsenic after sample digestion using AAS or ICP-MS. Control the total heavy metal limit according to pharmacopoeia general rules (e.g., ≤20 ppm). |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 128–132°C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.