1H-Pyrrolizine-7a(5H)-acetonitrile,tetrahydro-(9CI) Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 78449-75-9 |
| Product name | 1H-Pyrrolizine-7a(5H)-acetonitrile,tetrahydro-(9CI) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1H-Pyrrolizine-7a(5H)-acetonitrile,tetrahydro-(9CI)
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1H-Pyrrolizine-7a(5H)-acetonitrile,tetrahydro-(9CI) Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1H-Pyrrolizine-7a(5H)-acetonitrile,tetrahydro-(9CI)
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing antitumor bis-pyrrolidines | Used as a key chiral intermediate in multistep organic synthesis; employed in nucleophilic substitution or cyclization reactions to construct the target molecular scaffold |
Manufacturing Quality Control of 1H-Pyrrolizine-7a(5H)-acetonitrile,tetrahydro-(9CI)
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at characteristic wavelength, calibrated against reference standard. |
| Related Substances | HPLC-DAD | Separation and detection of impurities using gradient HPLC with diode-array detection for spectral confirmation and relative response factor correction. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on retention time and peak area. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for trace-level quantification of elemental impurities including Pb, Cd, Hg, As, and others. |
| Chloride Impurity | Ion Chromatography | Separation of anions on ion-exchange column with conductivity detection, using sodium carbonate/bicarbonate eluent. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of residual inorganic sulfate salts after acid treatment. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light source to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity under controlled lighting against defined standards. |
| pH of Aqueous Solution | pH Meter | Electrochemical measurement of hydrogen ion activity in a saturated aqueous suspension or dilute solution. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to calculate volume-based particle size distribution in dispersed powder sample. |
Technical Specifications of 1H-Pyrrolizine-7a(5H)-acetonitrile,tetrahydro-(9CI)
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic odor |
| Solubility | Miscible with common organic solvents |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1H-Pyrrolizine-7a(5H)-acetonitrile,tetrahydro-(9CI)
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1H-Pyrrolizine-7a(5H)-acetonitrile,tetrahydro-(9CI)
Safety Information of 1H-Pyrrolizine-7a(5H)-acetonitrile,tetrahydro-(9CI)
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1H-Pyrrolizine-7a(5H)-acetonitrile,tetrahydro-(9CI)
Industrial 1H-Pyrrolizine-7a(5H)-acetonitrile,tetrahydro-(9CI) Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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