Methyl 5-bromo-6-chloropyridine-3-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 78686-77-8 |
| Product name | Methyl 5-bromo-6-chloropyridine-3-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 5-bromo-6-chloropyridine-3-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 5-bromo-6-chloropyridine-3-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 5-bromo-6-chloropyridine-3-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a key building block for synthesizing biologically active nitrogen-containing heterocyclic compounds, such as protease inhibitors or receptor antagonists. |
| Pharmaceutical Chemicals | Molecular Building Blocks | Enables structural modification via cross-coupling reactions—including Suzuki coupling and Buchwald–Hartwig amination—leveraging the dibromo/dichloro functionality. |
| Agrochemicals | Agrochemical Intermediates | Used in the synthesis of active ingredients for novel neonicotinoid or other heterocyclic insecticides and fungicides. |
| Organic Synthesis | Functional Group Transformation Reagents | Facilitates preparation of corresponding carboxylic acids, alcohols, or amide derivatives via ester hydrolysis or reduction, supporting construction of complex molecular frameworks. |
Manufacturing Quality Control of Methyl 5-bromo-6-chloropyridine-3-carboxylate
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and presence of visible impurities under natural light or standard lighting conditions. |
| Purity (Active Ingredient Content) | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (e.g., 254 nm) to determine the content of the target compound via external standard or area normalization method. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Confirm the compound structure using ¹H-NMR and ¹³C-NMR by analyzing whether the characteristic peaks in proton and carbon spectra match the target structure. |
| Structure Confirmation | Mass Spectrometry (MS) | Use electrospray ionization (ESI) or electron impact (EI) mass spectrometry to determine the molecular ion peak ([M+H]+ or M⁺) for molecular weight confirmation. |
| Melting Point | Melting Point Determination | Measure the melting temperature of the sample using a melting point apparatus or capillary method to assess purity and consistency. |
| Water Content | Karl Fischer Titration | Accurately determine water content in the sample using a Karl Fischer titrator, suitable for trace moisture analysis. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or solution injection to detect organic solvents potentially residual from production (e.g., methanol, ethanol, dichloromethane). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate the main peak from impurity peaks using gradient elution to detect and quantify each related substance, evaluating the impurity profile of the sample. |
| Verification of Halogen Substituents | Elemental Analysis (EA) | Determine the elemental content of C, H, N, Br, and Cl in the sample and compare with theoretical values to verify molecular composition. |
| Crystal Form Analysis (if applicable) | X-ray Powder Diffraction (XRD) | Analyze the crystalline structure of solid samples for polymorph control or batch-to-batch consistency evaluation. |
Technical Specifications of Methyl 5-bromo-6-chloropyridine-3-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 5-bromo-6-chloropyridine-3-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 5-bromo-6-chloropyridine-3-carboxylate
Safety Information of Methyl 5-bromo-6-chloropyridine-3-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 5-bromo-6-chloropyridine-3-carboxylate
Industrial Methyl 5-bromo-6-chloropyridine-3-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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