China Factory Direct
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| CAS number | 78686-83-6 |
| Product name | METHYL 2-CHLORO-5-IODONICOTINATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing pyrethroid insecticides (e.g., fenpyroximate) | Constructs the target insecticide molecular scaffold via organic synthesis steps including nucleophilic substitution and coupling reactions |
| Pharmaceuticals | Synthesizes biologically active nitrogen-containing heterocyclic compounds, with potential application in anticancer or antiviral drug development | Acts as an aryl-heterocyclic building block in modern cross-coupling reactions such as Suzuki coupling and Buchwald-Hartwig amination |
| Fine Chemicals | Organic synthesis intermediate for preparing other functionalized nicotinic acid derivatives | Enables selective functional group transformations leveraging differential reactivity of iodine versus chlorine (e.g., iodine preferentially participates in metal-catalyzed coupling) |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at ~254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separates and detects impurities (e.g., starting materials, intermediates, dehalogenated/by-product species) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Quantifies volatile organic solvents (e.g., methanol, dichloromethane, toluene) by gas chromatography with flame ionization detection against calibrated standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Simultaneously quantifies trace heavy metals after acid digestion using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chlorine Content | Potentiometric Titration with AgNO₃ | Determines total organic chlorine via oxidative combustion followed by argentometric titration using silver nitrate and potentiometric endpoint detection. |
| Iodine Content | Oxidative Hydrolysis + Iodometric Titration | Releases iodide by alkaline hydrolysis, oxidizes to iodine, then titrates with standardized sodium thiosulfate using starch indicator. |
| Water Content | Karl Fischer Coulometric Titration | Measures trace water content electrochemically via iodine generation and coulometric quantification in anhydrous methanol-based reagent. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid phase transition using calibrated capillary apparatus per USP <741>. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (500–600 °C) and precise weighing. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity (if applicable) via rotation of plane-polarized light in solution using sodium D-line (589 nm). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.