1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI) Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 78703-53-4 |
| Product name | 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI) Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for novel herbicides, used in synthesizing pyrazole-based herbicides (e.g., halauxifen-methyl) | Undergoes palladium-catalyzed cross-coupling with haloarenes or heteroarenes, or derivatization reactions such as amidation and esterification with acyl chlorides/anhydrides to construct the active molecular core |
| Pharmaceuticals | Potential drug synthesis intermediate for constructing biologically active molecules containing a pyrazole scaffold (e.g., kinase inhibitor candidates) | Participates in cycloaddition, N-alkylation, and carboxyl-activated coupling reactions (e.g., EDC/HOBt-mediated condensation) to introduce pharmacophores or optimize ADME properties |
Manufacturing Quality Control of 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~220 nm. |
| Related Substances | HPLC-UV or HPLC-MS | Separation and quantification of structurally related impurities (e.g., starting materials, intermediates, degradation products) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual organic solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, As) after acid digestion, offering sub-ppt detection limits per ICH Q3D. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Anion separation and quantification (IC) or argentometric titration with silver nitrate endpoint detection. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Measurement of inorganic residue remaining after controlled high-temperature incineration and sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate. |
| Appearance and Color | Visual Inspection / Hazen (APHA) Color Scale | Subjective visual assessment against water or standardized color scale for clarity and yellowness. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine volumetric particle size distribution in dispersed dry or wet sample. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to assess chiral purity (if applicable; compound is achiral but method included for potential enantiomeric contaminants). |
Technical Specifications of 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148-152°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)
Safety Information of 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)
Industrial 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI) Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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