5-chloroquinazoline-2,4-diol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 78754-81-1 |
| Product name | 5-chloroquinazoline-2,4-diol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-chloroquinazoline-2,4-diol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-chloroquinazoline-2,4-diol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-chloroquinazoline-2,4-diol
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of anticancer agents (e.g., tyrosine kinase inhibitors) | Used to construct the quinazoline core; functional groups are introduced via nucleophilic substitution, coupling reactions, and related steps |
| Agrochemicals | Intermediate in the synthesis of plant growth regulators or fungicides | Participates in heterocyclic synthesis pathways; active ingredients are prepared through chlorine atom substitution or functional group transformation on the ring |
| Chemical Research | Organic building block for developing novel nitrogen-containing heterocyclic compounds | Structurally modified in the laboratory via acylation, alkylation, or transition-metal-catalyzed cross-coupling reactions |
Manufacturing Quality Control of 5-chloroquinazoline-2,4-diol
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold limits. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, DMF) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, using plasma emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode to detect endpoint based on AgCl precipitation potential shift. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs under controlled heating rate. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (600-700 C) to assess inorganic impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to calculate volume-based particle size distribution in dry or wet dispersion. |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume after standardized tapping to assess powder flow and packing characteristics. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Microbial Limits | Membrane Filtration | Quantification of aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) via filtration and agar culture. |
Technical Specifications of 5-chloroquinazoline-2,4-diol
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 248-252°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-chloroquinazoline-2,4-diol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-chloroquinazoline-2,4-diol
Packaging of 5-chloroquinazoline-2,4-diol
Industrial 5-chloroquinazoline-2,4-diol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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