(S)-1,4-N-Diboc-2-piperazine-2-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 788799-69-9 |
| Product name | (S)-1,4-N-Diboc-2-piperazine-2-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-1,4-N-Diboc-2-piperazine-2-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-1,4-N-Diboc-2-piperazine-2-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-1,4-N-Diboc-2-piperazine-2-carboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral building block for constructing piperazine-containing drug molecules | Participates in coupling reactions as a protected amino acid derivative in peptide synthesis, solid-phase synthesis, or liquid-phase organic synthesis |
| Medicinal Chemistry | Synthesis of biologically active piperazine compounds, including antiviral, antidepressant, and anticancer drug candidates | Selective deprotection and functionalization under Boc (tert-butoxycarbonyl) protection strategy |
| Organic Synthesis | Chiral auxiliary or intermediate for asymmetric synthesis | Stereoselective reactions guided by its chiral center, followed by deprotection to yield target chiral piperazine derivatives |
Manufacturing Quality Control of (S)-1,4-N-Diboc-2-piperazine-2-carboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with calibrated standard. |
| Chiral Purity | Chiral HPLC | Resolves (S)- and (R)-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak areas. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., THF, EtOAc, MeOH) using flame ionization detection after headspace or direct injection. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration based on iodine consumption in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pd, Ni, Fe) by mass spectrometry after acid digestion and dilution. |
| Residual Palladium | ICP-OES | Determines palladium catalyst residue by atomic emission spectroscopy following microwave-assisted acid digestion. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., deprotected intermediates, diastereomers) using gradient reverse-phase HPLC. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 589 nm to confirm chiral integrity and batch-to-batch consistency. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition as indicator of crystallinity and purity. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Measures volatile content (e.g., residual solvents, moisture) by weight loss after controlled heating under vacuum or air. |
| pH of Aqueous Suspension | pH Meter | Evaluates acidity/basicity by measuring pH of a defined suspension in water or water/isopropanol mixture. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using angular scattering intensity of laser light. |
Technical Specifications of (S)-1,4-N-Diboc-2-piperazine-2-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS); >=99% ee |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 145–149 °C |
| Optical Rotation | [α]D²⁰ = +28.5 to +31.5° (c = 1.0 in methanol) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-1,4-N-Diboc-2-piperazine-2-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-1,4-N-Diboc-2-piperazine-2-carboxylic acid
Safety Information of (S)-1,4-N-Diboc-2-piperazine-2-carboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-1,4-N-Diboc-2-piperazine-2-carboxylic acid
Industrial (S)-1,4-N-Diboc-2-piperazine-2-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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