China Factory Direct
|
|
| CAS number | 79-83-4 |
| Product name | D-PANTOTHENIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Food | Nutritional fortificant | Added to food products to supplement vitamin B5 |
| Feed | Feed additive | Incorporated into animal feed to support growth and health |
| Pharmaceuticals | Vitamin B5 supplement | Used in the manufacture of oral dosage forms, such as tablets and capsules |
| Cosmetics | Skin care products | Formulated into skin care products as a moisturizing and barrier-repairing ingredient |
| Biotechnology | Microbial fermentation medium | Employed in microbial cultivation and biosynthetic processes |
| Pharmaceutical intermediates | Synthesis of other pantothenic acid derivatives | Served as a precursor in the synthesis of coenzyme A and related compounds |
| Detection Item | Common Detection Methods | Method Overview |
|---|---|---|
| Assay | High-Performance Liquid Chromatography (HPLC) | Utilizes a reverse-phase C18 chromatographic column with a UV detector (typically at 200–210 nm wavelength), using mobile phases such as phosphate buffer-methanol to separate and quantify D-pantothenic acid from other components. This method offers high sensitivity and reproducibility, making it suitable for assay analysis in active pharmaceutical ingredients and formulations. |
| Microbiological Assay | Exploits the growth dependency of specific microorganisms (e.g., Lactobacillus plantarum) on D-pantothenic acid; quantification is achieved by measuring microbial growth (e.g., via absorbance). This method exhibits high specificity and is suitable for complex matrices, but is labor-intensive and time-consuming. | |
| Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) | Combines the separation capability of liquid chromatography with the high selectivity and sensitivity of mass spectrometry, particularly suited for accurate quantification of D-pantothenic acid at low concentrations or in complex matrices, commonly used in functional foods or biological samples. | |
| Impurity Analysis | High-Performance Liquid Chromatography (HPLC) | Optimized chromatographic conditions are employed to separate and detect related substances in D-pantothenic acid (e.g., degradation products, synthetic intermediates), with qualitative and quantitative analysis performed using UV or diode array detection to assess purity. |
| Thin-Layer Chromatography (TLC) | A traditional method used for preliminary impurity screening. Samples are spotted on a silica gel plate, developed, and visualized to detect impurity spots. Simple to perform but offers lower sensitivity and accuracy; primarily used for rapid screening. | |
| Water Content | Karl Fischer Titration | Based on the reaction of iodine and sulfur dioxide with water in an anhydrous environment to precisely determine water content. Available in volumetric and coulometric forms, this is the standard method for water content control in D-pantothenic acid raw materials. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Used to determine residual levels of heavy metals such as lead, arsenic, cadmium, and mercury. Samples are digested prior to analysis using AAS or ICP-MS to ensure compliance with pharmacopeial limits for heavy metals. |
| Residue on Ignition | Residue on Ignition Method | Sample is incinerated at high temperature until constant weight is achieved, and the residual non-volatile inorganic impurities are measured. Used to assess inorganic impurity levels in accordance with standards such as the Chinese Pharmacopoeia or USP. |
| pH Value | pH Meter Method | D-pantothenic acid is dissolved in water at a specified concentration (e.g., 1% solution), and its acidity or alkalinity is measured using a calibrated pH meter to control product stability and suitability. |
| Specific Optical Rotation | Polarimeter Method | Utilizes the optical activity of D-pantothenic acid; specific optical rotation is measured using a polarimeter at a specified wavelength (e.g., sodium D line, 589 nm) for identification and assessment of stereochemical purity. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 193°C - 196°C |
| Optical Rotation | +27° to +31° (c=2, in water) |
| Total Impurities | <=1.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.