China Factory Direct
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| CAS number | 79069-50-4 |
| Product name | Boc-L-alaninal |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a chiral synthon for constructing peptide-based therapeutics and small-molecule inhibitors | Introduction of the Boc-protected alaninal unit in solid-phase or solution-phase peptide synthesis; participates in coupling and reduction reactions |
| Organic Synthesis | Employed as a chiral aldehyde component in asymmetric synthesis to construct nitrogen-containing heterocycles or amino acid derivatives | Undergoes reductive amination with amines, addition with Grignard reagents, or carbon-chain elongation via Wittig or Horner-Wadsworth-Emmons reactions |
| Biochemical Research | Used to model enzyme active sites or design transition-state analog probes | Forms Schiff bases with lysine residues on proteins via the aldehyde group, or serves as a precursor for cysteine protease inhibitors |
| Chemical Reagents | Provides a Boc-protected α-aminoaldehyde structure for combinatorial library construction | Rapidly coupled to solid supports under microwave-assisted or flow chemistry conditions to generate diverse peptide-aldehyde libraries |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., Boc-D-alaninal, de-Boc alaninal, aldehyde oxidation products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Measures residual solvents (e.g., dichloromethane, ethyl acetate, methanol) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine generated electrochemically in presence of water. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC-UV | Separates enantiomers on a chiral stationary phase and calculates ee% from peak area ratio of L- vs D-form. |
| Heavy Metals | ICP-MS | Quantifies trace heavy metals (Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-OES | Measures palladium residues (from catalytic synthesis) after microwave digestion using inductively coupled plasma optical emission spectroscopy. |
| Acid Value | Acid-Base Titration | Determines free carboxylic acid impurities (e.g., from hydrolysis) by titration with standardized NaOH solution using phenolphthalein indicator. |
| Aldehyde Content | DNPH Derivatization HPLC-UV | Quantifies free aldehyde group via derivatization with 2,4-dinitrophenylhydrazine followed by HPLC-UV analysis of hydrazone adduct. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic residue after high-temperature ashing (700-800 C) and subsequent weighing. |
| Particle Size Distribution | Laser Diffraction | Determines solid particle size distribution in suspension using Mie scattering theory applied to laser diffraction data. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -32.0 to -28.0 deg (c=1, in CHCl3) |
| Melting Point | 78.0 to 82.0 °C |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.