China Factory Direct
|
|
| CAS number | 791-28-6 |
| Product name | Triphenylphosphine oxide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeElectronic GradeReagent GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Chemical Industry | Coordination reagent | Used as a ligand in transition metal-catalyzed coupling reactions, such as Suzuki coupling and Heck reactions |
| Pharmaceutical Industry | Pharmaceutical intermediate | Employed as an auxiliary reagent in organic synthesis to construct complex molecular frameworks |
| Materials Science | Fluorescent material preparation | Applied as an auxiliary reagent or structural building block in the synthesis of certain organic luminescent materials |
| Analytical Chemistry | NMR additive | Used in NMR analysis to enhance signal resolution for certain compounds |
| Environmental Science | Wastewater treatment | Applied for extraction and removal of heavy metal ions |
| Catalysis Technology | Oxidation reaction catalyst | Used as a catalyst or co-catalyst in oxidation reactions to improve selectivity and efficiency |
| Organic Synthesis | By-product of Wittig reactions | Formed as a by-product upon oxidation of phosphonium ylides in Wittig reactions; occasionally recovered and reused |
| Electronics Industry | Semiconductor material preparation | Used as a dopant or stabilizer in the synthesis of certain electronic materials |
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Utilizes a C18 reversed-phase column with methanol-water or acetonitrile-water as the mobile phase, detected by UV detector (254 nm). Quantification of TPPO content is performed using external standard or internal standard method, effectively separating impurities. |
| Impurity Profile Analysis | HPLC-MS (Liquid Chromatography-Mass Spectrometry) | Combines HPLC with mass spectrometry detection to identify and quantify organic impurities in TPPO (e.g., unreacted triphenylphosphine, oxidation by-products) through structural elucidation. |
| Water Content | Karl Fischer Titration | Employs Karl Fischer reagent (containing iodine, sulfur dioxide, pyridine, and methanol) to react quantitatively with water. Water content is determined via potentiometric or coulometric titration, suitable for high-precision moisture control (typically required < 0.5%). |
| Melting Point | Melting Point Apparatus | Determined using capillary method or automatic melting point instrument; literature value for TPPO is approximately 152–155°C, used for preliminary assessment of purity and detection of low-melting impurities. |
| Appearance and Color | Visual Inspection / Colorimetry | Sample appears as white to off-white crystalline powder with no visible mechanical impurities; colorimetric instruments (e.g., APHA or Pt-Co scale) may be used to quantitatively assess yellow index and control product color. |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace injection or direct injection GC-FID to detect common organic solvent residues such as ethanol, acetone, and ethyl acetate, meeting ICH Q3C guideline limits. |
| Ash/Inorganic Impurities | Ignition Residue Test (Sulfated Ash) | Sample is ignited at high temperature (500–600°C), and the residual inorganic matter is weighed to assess metal ions or inorganic salt impurities; typically requires ≤ 0.1%. |
| Phosphorus Content (Elemental Analysis) | Combustion-Colorimetric Method / ICP-OES | Organic phosphorus is converted into phosphate via high-temperature combustion, followed by molybdenum blue colorimetric determination; alternatively, total phosphorus content is directly measured using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) to verify molecular composition. |
| Solubility Verification | Solubility Determination | Measures solubility in common solvents (e.g., ethanol, diethyl ether, toluene, water) to confirm compliance with pharmacopoeial or company specifications, supporting batch consistency evaluation. |
| Crystal Form (Optional) | X-Ray Powder Diffraction (XRPD) | Used to confirm consistent crystal structure of TPPO, preventing issues related to stability or solubility caused by polymorphic variations; recommended for high-purity or pharmaceutical-grade products. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% (GC-MS) |
| Melting Point | 155–159°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.