4-bromo-1-iodo-2-methoxybenzene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 791642-68-7 |
| Product name | 4-bromo-1-iodo-2-methoxybenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-bromo-1-iodo-2-methoxybenzene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-bromo-1-iodo-2-methoxybenzene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-bromo-1-iodo-2-methoxybenzene
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in synthesizing complex aromatic drug molecules, such as kinase inhibitors or GPCR-targeting compounds | Serves as a versatile precursor in aryl halide cross-coupling reactions (e.g., Suzuki, Buchwald–Hartwig), enabling stepwise functionalization by leveraging the differential reactivity of bromine and iodine |
| Organic Synthesis Reagents | Constructs polysubstituted benzene scaffolds for natural product or functional material synthesis | Enables selective metal-catalyzed (e.g., Pd, Cu) substitution—iodine is preferentially replaced while bromine is retained for subsequent transformations, or vice versa—to control regioselectivity |
| Materials Science | Prepares optoelectronic materials or liquid crystal monomers containing methoxyphenyl motifs | Participates in Sonogashira or Heck coupling to introduce conjugated side chains; the methoxy group modulates electronic properties, while bromine/iodine sites direct molecular orientation and self-assembly behavior |
Manufacturing Quality Control of 4-bromo-1-iodo-2-methoxybenzene
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., bromination/isomerization by-products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, toluene, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-MS | Quantifies toxic elements (Pb, Cd, Hg, As) after acid digestion by inductively coupled plasma mass spectrometry with isotopic detection. |
| Residual Inorganic Salts | Ion Chromatography | Separates and quantifies anions (Cl-, Br-, SO42-) and cations (Na+, K+) using suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Appearance | Visual Inspection | Assesses physical state, color, and homogeneity of bulk material against established visual standards under controlled lighting. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring mass loss after drying at specified temperature and time under vacuum or nitrogen. |
| Chloride Impurity | Potentiometric Titration | Quantifies chloride ions using silver nitrate titrant and silver/silver chloride indicator electrode. |
| Iodine Content | Redox Titration | Determines total iodine via oxidation to iodate followed by iodometric back-titration with sodium thiosulfate. |
| Bulk Density | Tap Density Measurement | Measures mass per unit volume after standardized tapping; indicates flowability and packing behavior for handling and formulation. |
Technical Specifications of 4-bromo-1-iodo-2-methoxybenzene
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-bromo-1-iodo-2-methoxybenzene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-bromo-1-iodo-2-methoxybenzene
Safety Information of 4-bromo-1-iodo-2-methoxybenzene
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-bromo-1-iodo-2-methoxybenzene
Industrial 4-bromo-1-iodo-2-methoxybenzene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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