4-Propoxylmandelic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 79694-16-9 |
| Product name | 4-Propoxylmandelic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Propoxylmandelic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Propoxylmandelic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Propoxylmandelic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral intermediate for the synthesis of the antiplatelet drug ticagrelor | (S)-4-Propoxymandelic acid is produced via chiral resolution or asymmetric synthesis, followed by acid chloride formation and amination to construct the core structure of ticagrelor |
| Organic Synthesis | Chiral building block for constructing heterocyclic compounds and cardiovascular-active molecules containing chiral centers | Undergoes multi-step transformations—including esterification, reduction, halogenation, and coupling—commonly applied in the synthesis of quinazoline and pyrimidine derivatives |
Manufacturing Quality Control of 4-Propoxylmandelic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210–230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/DAD | Separation and identification of impurities using gradient HPLC with diode-array detection; qualification based on retention time and spectral match. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., propanol, ethyl acetate) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample. |
| Heavy Metals | ICP-MS | Quantification of elemental impurities (e.g., Pb, Cd, As, Hg) after acid digestion, per ICH Q3D requirements. |
| Optical Rotation | [α]D Measurement | Polarimetric measurement at 20 °C using sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by controlled heating; used for identity and purity assessment (sharpness and range). |
| Acid Value | Acid-Base Titration (NaOH, phenolphthalein) | Neutralization of carboxylic acid groups with standardized sodium hydroxide solution; indicates free acid content. |
| Residue on Ignition | Gravimetric Analysis | Incineration at 700–800 °C followed by weighing of inorganic residue; assesses inorganic ash content. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using light scattering to determine D10, D50, D90 values per USP <429>. |
Technical Specifications of 4-Propoxylmandelic acid
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 78–82°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Optical Rotation | -15° to -25° (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Propoxylmandelic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Propoxylmandelic acid
Packaging of 4-Propoxylmandelic acid
Industrial 4-Propoxylmandelic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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