China Factory Direct
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| CAS number | 79815-20-6 |
| Product name | (S)-(-)-Indoline-2-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeElectronic GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | As a pharmaceutical intermediate | Synthesizing drug molecules |
| Semiconductor Industry | For synthesizing organic semiconductor materials | Manufacturing organic electronic components |
| Materials Science | For synthesizing polymeric materials | Preparing polymers or liquid crystal materials |
| Fine Chemicals | Manufacturing fragrances, dyes, or agrochemicals | Synthesizing fragrances, dyes, or agrochemicals |
| Organic Synthesis | Constructing complex organic structures | Performing organic synthesis reactions |
| Test Item | Common Testing Method | Method Overview |
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| Appearance and Physical Characteristics | Visual Inspection, Physical Property Testing | Observe sample color and state (white or off-white crystalline powder), solubility (e.g., in water, ethanol), ensuring compliance with pharmacopoeial or internal quality standards. |
| Melting Point | Melting Point Apparatus | Determine melting range using capillary method or automatic melting point apparatus (typical range approximately 170–175°C) to assess purity and crystal form consistency. |
| Specific Rotation | Polarimetry | Prepare a solution of defined concentration (e.g., 1%) in methanol or water, measure specific rotation at 20°C. The (S)-isomer should show a characteristic negative value (e.g., [α]₂₀ᴰ = -100° to -120°), confirming optical purity. |
| Assay (Active Ingredient) | High-Performance Liquid Chromatography (HPLC) | Use C18 column, mobile phase of methanol-water (containing 0.1% formic acid or phosphate buffer), UV detection at 210–230 nm, calculate content by external standard method; requirement ≥98.0%. |
| Isomeric Impurity (R-Enantiomer) | Chiral HPLC | Employ chiral stationary phase columns (e.g., Chiralpak AD-H, OD-H) to separate (S) and (R)-enantiomers; detect R-isomer content, typically limited to ≤0.5%. |
| Water Content | Karl Fischer Titration | Determine trace moisture content by coulometric or volumetric Karl Fischer titration; control level ≤1.0% to ensure stability and storage safety. |
| Residual Solvents | Gas Chromatography (GC) | Use DB-624 or HP-INNOWAX column with FID detector to analyze residual solvents such as ethanol, methanol, ethyl acetate; comply with ICH Q3C guidelines. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine levels of heavy metals such as lead, cadmium, mercury, arsenic; meet pharmacopoeial limits (e.g., lead ≤5 ppm). |
| Sulfated Ash | Residue on Ignition Test | Ignite sample at high temperature (700–800°C), weigh the residue; limit ≤0.1%, to evaluate inorganic impurity levels. |
| pH Value (aqueous solution) | pH Meter Measurement | Prepare a 1% aqueous solution and measure pH (typically within range 4.5–6.5); reflects acidity/basicity and potential degradation products. |
| Microbial Limits (if applicable) | Total aerobic microbial count, mold/yeast count, specified pathogen testing | Conduct according to microbial limit tests in the Chinese Pharmacopoeia; applicable when API is used in oral formulations, must meet non-sterile pharmaceutical microbial standards. |
| Test Item | Specification |
|---|---|
| Appearance | White to light gray or light orange crystalline powder |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | -117.0 to -114.0 deg (c=1, in 1M HCl) |
| Melting Point | 148.0 to 152.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.