N-Boc-N'-benzyloxymethyl-L-histidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 79950-65-5 |
| Product name | N-Boc-N'-benzyloxymethyl-L-histidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Boc-N'-benzyloxymethyl-L-histidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Boc-N'-benzyloxymethyl-L-histidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Boc-N'-benzyloxymethyl-L-histidine
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Pharmaceutical intermediates | Used as a key intermediate in peptide synthesis for producing biologically active histidine derivatives |
| Biochemistry | Protecting reagent for peptide synthesis | Protects the histidine side chain during solid-phase peptide synthesis to prevent undesired side reactions |
| Pharmaceutical synthesis | Anticancer drug development | Applied in synthesizing peptide-based compounds targeting specific enzyme inhibitors for anticancer drug research |
| Medicinal chemistry | Molecular probe preparation | Used in synthesizing labeled or traceable probes for specific biomolecules to support drug target identification studies |
| Biotechnology | Synthesis of bioactive peptides | Employed as a protected amino acid derivative in synthesizing peptides with immunomodulatory or neuroactive functions |
Manufacturing Quality Control of N-Boc-N'-benzyloxymethyl-L-histidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210-220 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., de-Boc, de-benzyloxymethyl, or racemized forms) using gradient HPLC with UV detection. |
| Chiral Purity | Chiral HPLC | Enantioselective separation on a chiral stationary phase to determine L-enantiomer excess relative to D-isomer. |
| Residual Solvents | GC-FID | Quantitative determination of Class 2/3 residual solvents (e.g., DMF, DCM, MeOH, toluene) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to quantify water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic elements (Pb, Cd, Hg, As, Ni) after acid digestion and plasma ionization. |
| Residual Palladium | ICP-MS | Specific quantification of Pd residues from coupling catalysts using high-sensitivity mass spectrometry after microwave digestion. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration against established reference standards. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating purity and identity consistency. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and concentration. |
| Loss on Drying | Gravimetric Analysis | Weight loss upon controlled heating under vacuum or nitrogen, indicating volatile content including residual solvents and moisture. |
| pH of Solution | pH Meter | Measurement of aqueous suspension (e.g., 1% w/v in water) to assess acidic/basic impurities affecting stability and handling. |
Technical Specifications of N-Boc-N'-benzyloxymethyl-L-histidine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +6.5 to +7.5 deg (c=1, in 1M HCl) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Boc-N'-benzyloxymethyl-L-histidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Boc-N'-benzyloxymethyl-L-histidine
Safety Information of N-Boc-N'-benzyloxymethyl-L-histidine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-Boc-N'-benzyloxymethyl-L-histidine
Industrial N-Boc-N'-benzyloxymethyl-L-histidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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