5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 799842-07-2 |
| Product name | 5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 799842-07-2
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 799842-07-2 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 799842-07-2
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of sitagliptin | Participates in nucleophilic substitution or coupling reactions within the multi-step synthesis route for sitagliptin, enabling construction of the drug’s core molecular structure |
Manufacturing Quality Control of 799842-07-2
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and condition of the sample (e.g., white to off-white powder), whether it is clumped or contains visible impurities. |
| Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare the sample spectrum with a standard reference to confirm the presence of characteristic functional groups (e.g., C-Br, C-F, C=O, N-H, aromatic rings) through absorption peaks. |
| Nuclear Magnetic Resonance Spectroscopy (¹H NMR, ¹³C NMR) | Analyze the chemical environment of hydrogen and carbon atoms in the molecule using proton and carbon spectra to verify the correctness of the target compound's structure. | |
| High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) | Confirm the structure by comparing retention time and mass-to-charge ratio (m/z), particularly useful for identifying trace impurities or degradation products. | |
| Purity/Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase column (e.g., C18), UV detector (set at maximum absorbance wavelength, typically 254 nm or 220 nm), and calculate the main component content using external standard or area normalization methods. |
| Impurity Analysis | HPLC-DAD or UPLC-MS | Separate and detect related substances (e.g., synthetic intermediates, by-products, degradation products) using gradient elution and assess impurity levels based on response values. |
| Residual Solvents | Gas Chromatography (GC) | Detect volatile organic solvents used in the production process (e.g., methanol, ethanol, dichloromethane, ethyl acetate) according to ICH Q3C guidelines. |
| Moisture Content | Karl Fischer Titration | Accurately determine the moisture content in the sample, suitable for quality control of moisture-sensitive compounds. |
| Crystal Form Analysis | X-ray Powder Diffraction (XRD) | Identify different crystal forms and ensure consistency of crystalline structure across batches, which affects solubility and stability. |
| Differential Scanning Calorimetry (DSC) | Analyze melting point and thermal behavior to determine crystallinity, polymorphism, or the presence of solvates. | |
| Particle Size Distribution | Laser Diffraction (LD) | Determine the particle size distribution of solid particles, which influences dissolution rate and bioavailability of formulations. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Detect toxic elements such as lead, cadmium, mercury, and arsenic, complying with pharmacopoeia or ICH Q3D requirements. |
| Bromine Content Verification | Elemental Analysis (EA) or Ion Chromatography | Verify whether the theoretical bromine content matches, aiding in structural confirmation or impurity monitoring. |
Technical Specifications of 799842-07-2
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 799842-07-2
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 799842-07-2
Packaging of 799842-07-2
Industrial 799842-07-2 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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