Tetramethylguanidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 80-70-6 |
| Product name | Tetramethylguanidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeElectronic GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Tetramethylguanidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Tetramethylguanidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Tetramethylguanidine
| Industry | Applications | Process |
|---|---|---|
| Pharmaceuticals | Organic synthesis catalyst; pharmaceutical intermediate | Used as a strong, non-nucleophilic base in the synthesis of β-lactam antibiotics (e.g., cephalosporins) to promote condensation reactions |
| Agrochemicals | Insecticide and fungicide intermediate | Involved in cyclization and alkylation steps during the synthesis of novel triazole fungicides and pyrethroid insecticides |
| Materials Science | Polyurethane catalyst; epoxy resin curing accelerator | Acts as an efficient tertiary amine catalyst to accelerate the reaction between isocyanates and polyols; or co-catalyzes epoxy ring-opening polymerization with carboxylic acids |
| Electronic Chemicals | Photoresist additive; semiconductor cleaning aid | Modifies photoresist film-forming properties and development rate; serves as a buffering alkaline component in wafer cleaning solutions to control pH and chelate metal ions |
| Organic Synthesis | Strong, non-nucleophilic base catalyst; phase-transfer catalyst | Applied in base-sensitive reactions such as Claisen rearrangements, Dieckmann condensations, and silyl enol ether preparations; used in combination with quaternary ammonium salts to enhance phase-transfer efficiency |
Manufacturing Quality Control of Tetramethylguanidine
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe whether the sample is a colorless to slightly yellow transparent liquid, and check for suspended particles, precipitates, or foreign matter. |
| Content (Purity) | Gas Chromatography (GC) | Use capillary column gas chromatography with FID detector. Qualitative analysis based on retention time; quantitative analysis of TMG content via peak area normalization or external standard method. |
| High-Performance Liquid Chromatography (HPLC) | Suitable for thermally unstable samples. Uses reversed-phase C18 column with UV or refractive index detection. Quantitative analysis performed using a calibration curve. | |
| pH Value | pH Meter Method | Measure the pH of a defined concentration of TMG aqueous solution (e.g., 1% w/v) at 25°C using a pH meter to evaluate its proton-accepting capacity. |
| Moisture Content | Karl Fischer Titration | Accurately determine trace moisture in the sample using a Karl Fischer titrator, either volumetric or coulometric method. Suitable for moisture control in organic base compounds. |
| Density | Densimeter or Pycnometer Method | Measure mass per unit volume at a specified temperature (e.g., 20°C or 25°C) using a densimeter or pycnometer to assess batch consistency. |
| Refractive Index | Refractometry | Determine refractive index using an Abbe refractometer at standard temperature. Used as a physical constant for identification and preliminary purity screening. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from manufacturing (e.g., methanol, ethanol, acetone) according to pharmacopoeia or relevant standards, typically using headspace sampling. |
| Color | Platinum-Cobalt Colorimetric Method | Compare sample color against a standard platinum-cobalt color scale to assess degree of discoloration, indicating oxidation or impurity introduction. |
| Impurities (Related Substances) | LC-MS (Liquid Chromatography-Mass Spectrometry) | Separate and identify organic impurities in TMG, such as degradation products (e.g., dimethylamine, urea derivatives), enhancing sensitivity and accuracy of detection. |
| Alkalinity (Total Base Content) | Acid-Base Titration | Titrate TMG sample with standardized hydrochloric acid solution, using phenolphthalein indicator or potentiometric endpoint detection. Calculate total alkalinity to assess reactivity. |
Technical Specifications of Tetramethylguanidine
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=99.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.3% |
| Refractive Index (n20/D) | 1.432–1.436 |
| Relative Density (20°C/25°C) | 0.875–0.885 g/cm³ |
| Odor | Characteristic amine-like odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Tetramethylguanidine
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NMR Spectra of Tetramethylguanidine
Packaging of Tetramethylguanidine
Industrial Tetramethylguanidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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