China Factory Direct
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| CAS number | 80028-44-0 |
| Product name | ethyl pyrrolidine-3-carboxylate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Serves as a structural unit of tricyclic pyrrolidines for synthesizing degradase inhibitors (e.g., IDO inhibitors), enabling development of antitumor agents. |
| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Used to synthesize bioactive amide compounds, serving as a key raw material for preparing nitric oxide synthase (NOS) inhibitors and other pharmaceuticals. |
| Pharmaceutical Chemicals | Chiral Drug Development | Functions as a chiral building block for constructing drug molecules containing a pyrrolidine ring scaffold, supporting asymmetric synthesis research. |
| Organic Synthesis | Chemical Reagent | Leverages reactivity of the ethyl ester group and the pyrrolidine nitrogen atom to perform derivatization reactions—including amidation and reductive amination—for compound library construction. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Pyrrolidine-3-carboxylic Acid Ethyl Ester Hydrochloride) | HPLC with UV detection | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV absorbance at ~210 nm. |
| Related Substances | HPLC with UV detection | Separation and quantification of structurally similar impurities using gradient elution and UV detection, relative to the main peak. |
| Water Content | Karl Fischer titration | Electrochemical titration measuring water via reaction of iodine with sulfur dioxide in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 700-800 C. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) by plasma excitation and atomic emission spectroscopy. |
| Chloride Content | Potentiometric titration with silver nitrate | Titration based on formation of insoluble silver chloride, detected by silver ion-selective electrode. |
| pH (1% aqueous solution) | pH meter measurement | Direct potentiometric measurement of hydrogen ion activity in a defined aqueous solution. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light induced by chiral molecules in solution at specified concentration and path length. |
| Melting Point | Capillary melting point apparatus | Determination of temperature range over which solid transitions to liquid, observed visually or automatically. |
| Organic Volatile Impurities (Residual Solvents) | GC-FID | Separation and quantification of residual solvents (e.g., ethanol, ethyl acetate) using gas chromatography with flame ionization detection. |
| Appearance | Visual inspection | Assessment of physical state, color, and clarity against standard references under controlled lighting. |
| Particle Size Distribution | Laser diffraction | Analysis of particle size based on angular dependence of laser light scattering in a dispersed sample. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.