1-Hydroxybenzotriazole hydrate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 80029-43-2 |
| Product name | 1-Hydroxybenzotriazole hydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Hydroxybenzotriazole hydrate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Hydroxybenzotriazole hydrate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Hydroxybenzotriazole hydrate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Condensation promoter in peptide synthesis to enhance coupling efficiency and suppress racemization | Used in conjunction with carbodiimide reagents (e.g., DCC, EDC) in solid-phase or solution-phase peptide synthesis to activate carboxyl groups and form active ester intermediates |
| Pharmaceutical Intermediates Synthesis | Multifunctional hydroxyl protecting/activating reagent for heterocycle modification | Serves as a structural unit in benzotriazole derivative synthesis, enabling introduction of specific functional groups via O-alkylation or O-acylation |
| Materials Science | Dopant additive in electron transport layers of organic light-emitting diode (OLED) devices | Coevaporated with metal complexes or solution-processed via spin coating to improve thin-film morphology and charge-carrier mobility |
Manufacturing Quality Control of 1-Hydroxybenzotriazole hydrate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, comparing peak area against a certified reference standard. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in methanol-based solvent. |
| Residue on Ignition | Gravimetric Analysis | Heating sample to 700-800 C to combust organic matter, then weighing inorganic residue. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification of trace metals after acid digestion, based on atomic emission intensity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection. |
| Related Substances | HPLC-UV | Detection and quantification of structurally similar impurities using gradient HPLC with UV detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under standardized lighting. |
| Solubility in Water | Qualitative Solubility Test | Evaluation of complete dissolution in specified volume of water at 25 C with agitation. |
| pH of Aqueous Solution | pH Meter | Measurement of hydrogen ion activity in a saturated aqueous suspension using calibrated pH electrode. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss determination after drying at 105 C for 2 hours under atmospheric pressure. |
| Microbial Limits | Membrane Filtration | Quantitative enumeration of aerobic microorganisms following filtration and agar culture incubation. |
Technical Specifications of 1-Hydroxybenzotriazole hydrate
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 102-106°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Hydroxybenzotriazole hydrate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Hydroxybenzotriazole hydrate
Safety Information of 1-Hydroxybenzotriazole hydrate
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 1-Hydroxybenzotriazole hydrate
Industrial 1-Hydroxybenzotriazole hydrate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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