5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 80076-46-6 |
| Product name | 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as an organic synthesis intermediate for preparing bioactive compounds | Prepared via multi-step organic synthesis reactions, including fluorination and cyclization |
| Pharmaceuticals | Applied in the development of central nervous system drugs, such as antidepressants and anxiolytics | Serves as a key intermediate in constructing the drug molecule structure |
| Pesticides | Used to synthesize certain fluorinated pesticide intermediates | Synthesized via fluorination and cyclization processes |
| Advanced Materials | Applied in synthesizing specialty functional materials or polymer monomers | Produced via fine chemical synthesis processes |
Manufacturing Quality Control of 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with standard spectra to confirm whether the characteristic peaks of molecular functional groups are consistent. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Obtain information on chemical shifts, coupling constants, and other parameters of hydrogen atoms to verify structural characteristics. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with an appropriate mobile phase (e.g., methanol/water or acetonitrile/buffer salt) for separation, and quantify the main component using a UV detector. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Similar conditions as content determination, but optimize gradient elution programs to separate and quantitatively analyze potential impurities (e.g., starting materials, intermediates, degradation products). |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with polar or non-polar capillary columns and FID detection to determine residual organic solvents (e.g., methanol, dichloromethane, DMF) from synthesis processes. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Constant Temperature Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved; calculate the percentage of mass loss to assess moisture and volatile content. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range using capillary tube method or digital melting point instrument as a reference indicator for purity and polymorphic form. |
| Specific Rotation (if applicable) | Polarimeter | Although the compound is racemic (±), if verification of its racemic nature is required, the specific rotation should be close to 0°, confirming no enantiomeric enrichment. |
| pH Value (if in solution formulation) | pH Meter | Prepare a solution of the sample at a defined concentration and measure its acidity or alkalinity using a calibrated pH meter to evaluate stability or compatibility with excipients. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine the residual levels of heavy metals such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeial or ICH Q3D limits. |
Technical Specifications of 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 124.0–128.0 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -15.0 to +15.0 ° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline
Industrial 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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