China Factory Direct
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| CAS number | 80194-68-9 |
| Product name | 3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Insecticide intermediate | Used in the synthesis of high-efficiency insecticides, such as flonicamid and other neonicotinoid compounds, via coupling or esterification reactions to introduce bioactive structures |
| Pharmaceuticals | Drug synthesis intermediate | Serves as a building block for fluorinated pyridine-based drugs, employed in the research and synthesis of anti-inflammatory and antitumor agents |
| Fine chemicals | Organic synthesis intermediate | Applied in the preparation of functional fluorinated aromatic compounds for materials science and functional molecule design |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 220-254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents (e.g., methanol, acetone, toluene) using gas chromatography with flame ionization detection and headspace sampling. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water content via iodine-sulfur dioxide reaction in anhydrous pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, based on mass-to-charge ratio detection with isotopic resolution. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium residues post-catalytic synthesis by plasma excitation and optical emission intensity measurement. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary tube method per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in suspension via Mie scattering theory analysis of laser diffraction patterns. |
| Specific Optical Rotation | Polarimetry | Measurement of chiral rotation of plane-polarized light in solution at specified concentration, temperature, and wavelength (e.g., 20 degrees C, 589 nm). |
| pH of Aqueous Slurry | Potentiometric pH Measurement | Determination of slurry pH using calibrated glass electrode in a saturated aqueous suspension per EP 2.2.3. |
| Residue on Ignition | Gravimetric Analysis | Quantification of inorganic ash content after high-temperature incineration (600-800 degrees C) and weighing of residual residue. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.