2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 80443-63-6 |
| Product name | 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antidepressant venlafaxine | Prepared via epoxidation in organic synthesis; subsequently employed in ring-opening and amination steps to construct the venlafaxine molecular scaffold |
| Fine Chemicals | Synthesis of structurally defined nitrogen-containing heterocyclic compounds | Used as an ethylene oxide-based building block; reacts with amine nucleophiles under acidic or basic conditions to yield β-amino alcohol derivatives |
Manufacturing Quality Control of 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane
| Detection Item | Common Detection Methods | Method Overview |
|---|---|---|
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (¹H NMR, ¹³C NMR) | Confirm the molecular framework through characteristic peaks in proton and carbon spectra, such as epoxy ring protons (δ 2.5–3.2 ppm), aromatic protons (δ 7.2–7.4 ppm), and tertiary butyl signals (δ 1.2 ppm), by comparing with standard spectra. |
| Infrared Spectroscopy (FT-IR) | Detect characteristic absorption peaks of epoxide (approximately 820–850 cm⁻¹, asymmetric C–O–C stretching) and chlorophenyl C–Cl stretching (approximately 750–800 cm⁻¹). | |
| Mass Spectrometry (MS, ESI or EI) | Confirm molecular weight (theoretical value ~224.7) through molecular ion peak [M+H]⁺ or [M]⁺, and analyze fragment ions to verify the structure (e.g., loss of –C₄H₉, ring-opening fragments, etc.). | |
| Purity Determination | High-Performance Liquid Chromatography (HPLC) | Use a C18 column, gradient elution with water-acetonitrile, UV detection (220–254 nm), calculate the area percentage of the main peak to assess chemical purity and detect known or unknown impurities. |
| Gas Chromatography (GC) | Used for volatile impurity detection, such as residual solvents or low-molecular-weight byproducts; use a polar column (e.g., DB-WAX) for separation and FID detection. | |
| Organic Impurity Analysis | HPLC-MS Coupling Technology | Combine HPLC separation with mass spectrometry identification to identify and quantify structurally related impurities (e.g., ring-opening alcohols, dimers, unreacted raw materials). |
| Residual Solvents | Gas Chromatography (GC-FID/MS) | Detect common organic solvent residues (e.g., ethanol, acetone, dichloromethane, acetonitrile) using headspace sampling according to ICH Q3C guidelines, with quantitation limits at the ppm level. |
| Water Content | Karl Fischer Titration (Karl Fischer) | Accurately determine trace water content (typically <0.5%), suitable for water-sensitive epoxide compounds. |
| Chlorine Content | Combustion Ion Chromatography (CIC) or ICP-MS | Determine chlorine ion content after complete combustion of the sample, or directly measure total chlorine using inductively coupled plasma mass spectrometry, verifying the presence and content of chlorine atoms. |
| Heavy Metal Residues | ICP-MS or ICP-OES | Detect toxic heavy metals such as lead, cadmium, mercury, and arsenic, complying with pharmaceutical-grade standards (e.g., ICH Q3D), suitable for raw material-level control. |
| Isomer/Stereoisomer Analysis | Chiral HPLC or GC | If there are chiral centers (e.g., chiral structure of the epoxy ring), separate enantiomers using a chiral stationary phase column (e.g., Chiralpak AD/AS) and determine ee value. |
| Stability Indicating Method | Accelerated Degradation Test + HPLC | Accelerate degradation under high temperature, high humidity, strong light, acid, and alkaline conditions, monitor the degradation products of the main component, and establish a stability-indicating method for determining shelf life. |
| Melting Point/Boiling Point | Melting Point Apparatus or Boiling Point Apparatus | Physical constants for identification (if solid, melting range can be used as a quality indicator; if liquid, determine boiling point range). |
Technical Specifications of 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane
| Test Item | Specification |
|---|---|
| Appearance | Light yellow to orange clear liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Refractive Index (n20/D) | 1.540–1.550 |
| Relative Density (20°C/25°C) | 0.98–1.02 g/cm³ |
| Odor | Characteristic mild organic odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane
Safety Information of 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane
Industrial 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply