China Factory Direct
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| CAS number | 80657-57-4 |
| Product name | METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediate for synthesis of pharmaceuticals (e.g., β-lactam antibiotics) | Used in asymmetric synthesis and esterification |
| Fine Fragrances | Synthesis of flavor and fragrance compounds with fruity or creamy notes | Applied in catalytic hydrogenation and transesterification |
| Organic Synthesis | Chiral building block for constructing complex molecules (e.g., total synthesis of natural products) | Employed in enzymatic catalysis and chemical resolution |
| Agricultural Chemicals | Intermediate for synthesis of chiral pesticides or plant growth regulators | Utilized in condensation reactions and optical purification |
| Materials Science | Monomer for biodegradable polymers (e.g., polyhydroxyalkanoates, PHA) | Applied in ring-opening polymerization and enzymatic polymerization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies main component using retention time and peak area against reference standard. |
| Enantiomeric Excess (ee) | Chiral Gas Chromatography (cGC) | Separates (S)- and (R)-enantiomers on chiral stationary phase; ee calculated from peak area ratio. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in methanol-based solvent. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Detects volatile solvents (e.g., methanol, toluene) by equilibrium partitioning into headspace before GC analysis. |
| Acid Value | Acid-Base Titration with NaOH | Measures free acid impurities by titration with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Specific Optical Rotation | [a]D Measurement using Polarimeter | Determines optical activity at 589 nm to confirm chiral integrity and identity of (S)-(+)-enantiomer. |
| Heavy Metals | ICP-OES | Quantifies trace metals (e.g., Pb, Cd, Ni) after acid digestion by plasma emission spectroscopy. |
| Chloride Content | Ion Chromatography (IC) | Separates and quantifies chloride ions based on anion exchange and conductivity detection. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established visual standards under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing and weighing. |
| Related Substances | HPLC with UV Detection | Identifies and quantifies structurally related impurities using reversed-phase chromatography and UV absorbance. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, confirming identity and purity. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.5% (GC-MS); >=99.0% ee |
| Optical Rotation | +22.3 to +22.7 (c=1, in CHCl3) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.428 to 1.432 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.