China Factory Direct
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| CAS number | 81-25-4 |
| Product name | Cholic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Non-surgical dissolution of gallstones | Raw material or intermediate for the synthesis of ursodeoxycholic acid (UDCA) or chenodeoxycholic acid (CDCA) |
| Pharmaceuticals | Treatment of bile-deficient dyspepsia | Choleretic agent component to promote bile secretion |
| Pharmaceuticals | Treatment of cholestatic liver disease | Modulation of hepatobiliary function |
| Chemicals | Biochemical reagent | Reference standard or control substance in biochemical research |
| Chemicals | Synthesis of surfactants | Synthesis of zwitterionic surfactants |
| Cosmetics | Skin care ingredient | Moisturizing and skin-repairing additive |
| Test Item | Common Testing Methods | Method Overview |
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| Cholic Acid | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase column (e.g., C18) and a UV detector (typically 200–210 nm). Cholic acid is identified and quantified by comparing retention times and peak areas with reference standards. Suitable for content determination and impurity testing of cholic acid in raw materials and formulations. |
| Cholic Acid | Thin-Layer Chromatography (TLC) | Employs silica gel G plates and an appropriate developing solvent (e.g., ethyl acetate-methanol-water). After development and visualization, spot positions and intensities are examined for qualitative identification and preliminary purity assessment. Simple to perform but has relatively low sensitivity. |
| Cholic Acid | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Measures the UV absorption of cholic acid at specific wavelengths (around 200–210 nm). Content is determined using a standard curve method. Suitable for estimating cholic acid concentration in crude products or formulations. However, it lacks specificity and is prone to interference. |
| Cholic Acid | Mass Spectrometry (LC-MS) | Couples liquid chromatography separation with mass spectrometric detection, providing molecular ion and fragment information. Used for structural confirmation, trace analysis, and metabolite identification of cholic acid. Offers high sensitivity and specificity; commonly applied in research or analysis of complex samples. |
| Cholic Acid | Enzymatic Method | Utilizes specific enzymes such as 3α-hydroxysteroid dehydrogenase (3α-HSD) to catalyze redox reactions of cholic acid. The concentration is determined by measuring changes in absorbance of coenzymes. Ideal for detecting cholic acid in biological samples (e.g., serum, bile), offering good selectivity and minimal interference. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid or chunks |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 192–197 °C |
| Optical Rotation | +33 to +37 ° (c=1, in 0.1N NaOH) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.