China Factory Direct
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| CAS number | 81-93-6 |
| Product name | Phenosafranin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antimalarial drugs chloroquine and hydroxychloroquine | Prepared via condensation of 4,7-dichloroquinoline with ethyl 2-amino-5-diethylaminopentanoate, followed by cyclization, hydrolysis, and esterification to yield quinodimethylester |
| Pharmaceuticals | Used in the preparation of other quinoline-derived pharmaceuticals (e.g., anti-amebic agents) | Serves as a C2-functionalized precursor of the quinoline core, participating in nucleophilic substitution or palladium-catalyzed cross-coupling reactions |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard under specified chromatographic conditions. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water content via iodine-sulfur dioxide reaction in a methanol-based solvent system. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution, with phenolphthalein endpoint detection. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 500-600 C and subsequent weighing. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantification of total heavy metals after wet digestion, based on absorption of characteristic atomic spectral lines. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using an anion-exchange column and conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Determination of inorganic residue after sulfuric acid treatment followed by ignition and weighing. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard references under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Determination | Thermal transition measurement using calibrated apparatus; onset and completion temperatures recorded. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity. |
| Organic Volatile Impurities | Headspace Gas Chromatography-Mass Spectrometry (HS-GC-MS) | Identification and quantification of residual solvents and volatile impurities via thermal desorption and mass spectral detection. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of structurally related impurities using reversed-phase chromatography and UV absorbance at 220 nm. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 138-142°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.