China Factory Direct
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| CAS number | 81228-09-3 |
| Product name | 2,4-Difluorophenylacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antibiotic intermediates | Used in synthetic routes for specific antibiotics |
| Pesticides | Insecticide/fungicide intermediates | Serves as a raw material for synthesizing high-efficiency insecticides or fungicides |
| Chemical materials | Raw material for specialty chemicals | Used to produce high-performance polymers or additives |
| Food additives | Food preservatives | Acts as a synthetic precursor for food preservatives |
| Dyes | Dye intermediates | Key raw material for synthesizing novel dyes |
| Test Item | Common Testing Method | Method Description |
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| Identification Test | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with standard spectra to confirm the presence of characteristic functional groups in 2,4-difluorophenylacetic acid (e.g., carboxylic acid, aromatic rings, C–F bonds, etc.). |
| Nuclear Magnetic Resonance Hydrogen Spectrum (¹H NMR) | Use nuclear magnetic resonance technology to analyze the chemical shifts, integration areas, and coupling constants of hydrogen atoms in the sample. Compare the results with theoretical spectra to verify the molecular structure. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 chromatographic column with methanol/water or acetonitrile/water as the mobile phase. Detect using a UV detector (typically at 220–254 nm wavelength) and calculate the content of the main component using external standard or internal standard methods. |
| Acid-Base Titration Method | Utilize the carboxylic acid property of 2,4-difluorophenylacetic acid and titrate with sodium hydroxide standard solution using potentiometric or indicator titration to calculate its acid value or purity. | |
| Related Substances (Impurities) Check | High-Performance Liquid Chromatography (HPLC) | Use gradient elution or isocratic elution programs to separate and detect possible synthetic intermediates, by-products, or degradation products. Quantify them using area normalization method or the principal component self-reference method with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | Following ICH Q3C guidelines, use headspace injection or direct injection methods to separate solvents via capillary columns and detect common organic solvents (e.g., methanol, ethanol, dichloromethane, etc.) with an FID detector to determine their residual amounts. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Weight Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, then measure the percentage loss in mass due to moisture or other volatile components. |
| Melting Point | Capsule Melting Point Determination Method | Use a melting point apparatus to measure the temperature range from initial melting to complete melting and compare it with literature values (approximately 98–102°C) to evaluate purity and crystal form consistency. |
| Water Content | Karl Fischer Titration | Titrate water content in the sample using Karl Fischer reagent with high specificity, suitable for trace water determination, providing accurate and reliable results. |
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 126.0 - 130.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.