China Factory Direct
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| CAS number | 81246-82-4 |
| Product name | 5'-DMT-RIBO ADENOSINE (N-BZ) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Used in the synthesis of nucleotide analogs as protecting groups for DNA/RNA synthesis | Applied in solid-phase oligonucleotide synthesis as a protected adenosine derivative, providing protection at the 5'-O and N6 positions to facilitate subsequent coupling reactions |
| Organic Synthesis | Intermediate for synthesizing nucleoside-based compounds | Enables construction of complex nucleoside structures via selective deprotection and coupling reactions |
| Molecular Biology | Preparation of fluorescently labeled or functionalized oligonucleotides | Introduces specific functional groups during oligonucleotide synthesis to support probe or drug molecule design |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at 260 nm using reverse-phase C18 column and gradient elution with acetonitrile/buffer mobile phase. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities (e.g., desilylated, deacylated, or hydrolyzed analogs) using optimized HPLC separation and UV detection. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., DCM, DMF, MeOH) by gas chromatography with flame ionization detection and headspace sampling. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine-based reagent reacting stoichiometrically with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Hg, Ni) by inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Residual Chloride | Ion Chromatography | Measures chloride ion concentration using anion-exchange column with suppressed conductivity detection after sample dissolution. |
| Optical Rotation | [alpha]D Measurement | Determines specific optical rotation at 589 nm using a polarimeter to confirm chiral integrity and identity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating purity and crystallinity. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in suspension using Mie scattering theory and laser diffraction optics. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
| Residual Triphenylmethanol | HPLC-UV | Quantifies triphenylmethanol, a common synthesis byproduct, using reversed-phase HPLC with UV detection at 270 nm. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode and pH meter. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -11.5 to -10.9° (c=1, in CHCl3) |
| Melting Point | 178–182°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.