China Factory Direct
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| CAS number | 81449-93-6 |
| Product name | ETHYL 2-CHLOROTHIAZOLE-5-CARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Agrochemicals | Key intermediate for neonicotinoid insecticides such as clothianidin and thiamethoxam | Prepared via hydrolysis and acid chlorination to yield 2-chloro-5-(chloromethyl)thiazole or thiazole-5-carbonyl chloride, followed by condensation with amines to construct the insecticidal molecular scaffold |
| Agrochemicals | Precursor for synthesizing the insecticidal intermediate 2-chloro-5-(aminomethyl)thiazole | Ester group reduced (e.g., via catalytic hydrogenation) to hydroxymethyl, followed by halogenation and amination to produce the intermediate |
| Pharmaceuticals | Building block for thiazole-containing drug molecules | The carboxylate ester functionality on the thiazole ring is used in coupling, reduction, or hydrolysis reactions to construct biologically active drug structures |
| Organic Synthesis | Functional intermediate for thiazole derivatives | Subjected to nucleophilic substitution or hydrolysis to prepare corresponding carboxylic acids, amides, or alcohols for fine chemical synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against qualified impurity standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., ethanol, toluene, DMF) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion, measuring emission intensities of metals (Pb, Cd, Hg, As, Ni) against calibration curves. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint detected by abrupt potential change due to AgCl precipitation. |
| Acid Value | Acid-Base Titration | Neutralization of acidic impurities with standardized NaOH solution using phenolphthalein indicator or potentiometric endpoint detection. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, using calibrated digital apparatus per USP <741>. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (600-800 C) to determine inorganic non-volatile content. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as a function of angle to calculate volume-based particle size distribution in dispersed suspension. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity and enantiomeric excess. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78-82°C |
| Identification (IR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic mild odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.