Z-Pyr-OtBu Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 81470-51-1 |
| Product name | Z-Pyr-OtBu |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Z-Pyr-OtBu
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Z-Pyr-OtBu Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Z-Pyr-OtBu
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Protecting group reagent for selective protection of the side-chain carboxyl groups of glutamic acid or aspartic acid in peptide synthesis | Introduced under basic conditions in solid-phase peptide synthesis (SPPS) to form a stable tert-butyl ester protecting group; removed subsequently via acidolysis (e.g., with TFA) |
| Peptide Chemistry | Synthesis of peptide fragments containing pyroglutamic acid | Condensed with amino components using Z-Pyr-OTBu to construct an N-terminal pyroglutamic acid residue, enabling mimicry of native bioactive peptides or enhancement of metabolic stability |
| Biochemical Research | Building block for enzyme inhibitors or receptor ligands | Used as a synthetic building block in solution-phase or solid-phase synthesis to develop small-molecule probes targeting specific proteases or neurotransmitter receptors |
Manufacturing Quality Control of Z-Pyr-OtBu
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., THF, MTBE, heptane) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification after acid digestion, using isotopic detection for high sensitivity and selectivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after controlled high-temperature incineration and weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP <741>. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed sample via light scattering to determine volume-weighted particle size distribution. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined saturated aqueous suspension using calibrated electrode per EP 2.2.3. |
| Microbial Limits | Membrane Filtration | Quantitative enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
Technical Specifications of Z-Pyr-OtBu
| Test Item | Specification |
|---|---|
| Appearance | White Solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 78–82°C |
| Optical Rotation | -64.0 to -63.0° (c=1, in CHCl3) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Z-Pyr-OtBu
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Z-Pyr-OtBu
Packaging of Z-Pyr-OtBu
Industrial Z-Pyr-OtBu Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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