2-Chloro-4-(trifluoromethyl)pyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 81565-18-6 |
| Product name | 2-Chloro-4-(trifluoromethyl)pyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-4-(trifluoromethyl)pyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-4-(trifluoromethyl)pyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-4-(trifluoromethyl)pyridine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing insecticides, herbicides, and fungicides—e.g., used in the preparation of novel neonicotinoid insecticides such as flonicamid | Converted into target active ingredients via organic synthesis steps including nucleophilic substitution, coupling reactions, or reduction |
| Pharmaceuticals | Structural building block for drug molecules; employed in synthesizing bioactive pyridine-containing compounds, including anticancer, antiviral, and central nervous system drug candidates | Undergoes arylation, amination, or metal-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald–Hartwig) in medicinal chemistry synthesis, leveraging the reactivity of its chlorine atom |
| Chemical Research | Organic synthesis reagent and building block for developing novel fluorinated heterocyclic compounds | Trifluoromethylpyridine scaffold introduced via transition-metal catalysis, radical reactions, or electrochemical methods for structure–activity relationship studies or new material exploration |
Manufacturing Quality Control of 2-Chloro-4-(trifluoromethyl)pyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Related Substances | Gas Chromatography-Mass Spectrometry (GC-MS) | Identification and quantification of impurities by retention time and characteristic mass fragmentation patterns. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile organic solvents are vaporized in sealed vials and quantified via GC-FID using calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically. |
| Acidity (as HCl) | Acid-Base Titration with NaOH | Neutralization of acidic impurities (e.g., residual HCl) using standardized sodium hydroxide solution and potentiometric endpoint detection. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES) | Multi-element quantification after acid digestion, based on element-specific atomic emission intensities. |
| Chloride Ion | Ion Chromatography (IC) with conductivity detection | Separation of anions on an ion-exchange column followed by quantitative detection via suppressed conductivity. |
| Residue on Ignition | Gravimetric Analysis | Mass of non-volatile inorganic residue determined after controlled high-temperature ashing of sample. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition temperature measured by observing solid-to-liquid phase change under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral impurities or enantiomeric excess (if applicable). |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Bulk Density | Tap Density Tester | Determination of mass per unit volume after standardized mechanical tapping of a known powder mass in a graduated cylinder. |
Technical Specifications of 2-Chloro-4-(trifluoromethyl)pyridine
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Refractive Index (n20/D) | 1.435–1.445 |
| Relative Density (20°C/25°C) | 1.380–1.395 g/cm³ |
| Odor | Characteristic pyridine-like odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-4-(trifluoromethyl)pyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-4-(trifluoromethyl)pyridine
Safety Information of 2-Chloro-4-(trifluoromethyl)pyridine
| Pictograms |   |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Chloro-4-(trifluoromethyl)pyridine
Industrial 2-Chloro-4-(trifluoromethyl)pyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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