Methyl 4-methyl-5-thiazolecarboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 81569-44-0 |
| Product name | Methyl 4-methyl-5-thiazolecarboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 4-methyl-5-thiazolecarboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 4-methyl-5-thiazolecarboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 4-methyl-5-thiazolecarboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key intermediate for the antiplatelet drug ticagrelor | Serves as a thiazole ring building block; incorporated into the drug molecule scaffold via hydrolysis, amidation, or coupling reactions |
| Pharmaceutical Chemicals | Synthesis of active pharmaceutical ingredients (APIs) and advanced intermediates | Leverages its ester group and thiazole ring for functional group transformations—e.g., reduction to alcohol or aldehyde—to prepare other pharmaceutically active molecules |
| Organic Synthesis | Building block for thiazole derivatives | Used in heterocyclic synthesis as a reagent in cross-coupling or substitution reactions to introduce the 4-methylthiazole moiety |
Manufacturing Quality Control of Methyl 4-methyl-5-thiazolecarboxylate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by retention time and UV absorbance relative to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, THF) via flame ionization detection after headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water by electrochemical titration with iodine-based reagent in anhydrous methanol. |
| Heavy Metals | ICP-OES | Quantifies elemental impurities (Pb, Cd, Hg, As, etc.) after acid digestion using plasma optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separates and quantifies sulfate ions using suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration and weighing of residue. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against established reference standards under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light induced by chiral centers in solution. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines hydrogen ion activity in a saturated aqueous suspension using calibrated pH electrode. |
Technical Specifications of Methyl 4-methyl-5-thiazolecarboxylate
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C - 132°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 4-methyl-5-thiazolecarboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 4-methyl-5-thiazolecarboxylate
Safety Information of Methyl 4-methyl-5-thiazolecarboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 4-methyl-5-thiazolecarboxylate
Industrial Methyl 4-methyl-5-thiazolecarboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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