2-Bromo-5-chlorophenylacetic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 81682-38-4 |
| Product name | 2-Bromo-5-chlorophenylacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Bromo-5-chlorophenylacetic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Bromo-5-chlorophenylacetic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Bromo-5-chlorophenylacetic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of antihypertensive drugs (e.g., losartan derivatives) | Undergoes nucleophilic substitution with amines under basic conditions to construct the biphenyl tetrazole structure |
| Agrochemical Intermediates | Modifies the phenyl ring as a substituent in the preparation of novel insecticides and fungicides | Introduces functionalized side chains via palladium-catalyzed cross-coupling reactions (e.g., Suzuki coupling) |
| Organic Synthesis | Acts as a versatile aryl halide in organometallic reactions | Converted to organolithium or Grignard reagents, followed by borylation, for C–C bond formation |
Manufacturing Quality Control of 2-Bromo-5-chlorophenylacetic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, relative to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and peak area normalization. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection for quantification of common solvents (e.g., methanol, acetone, ethyl acetate) against calibration standards. |
| Moisture Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine generated electrochemically or added reagent to quantify water content based on stoichiometric reaction. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element detection after acid digestion; quantification by atomic emission intensity at characteristic wavelengths relative to calibration curves. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with conductivity detection; quantification using chloride standard calibration. |
| Residual Palladium | ICP-MS | Ultra-trace quantification after microwave-assisted acid digestion using mass spectrometric detection of Pd isotopes (e.g., 105Pd, 106Pd). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually in a capillary tube; determined as the temperature range over which solid-to-liquid phase change occurs. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using sodium D-line light in solution; indicates enantiomeric purity if chiral impurities are present. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to calculate volume-based particle size distribution in dispersed powder sample. |
| Bulk Density | Tap Density Tester | Determination of mass per unit volume after controlled tapping of a known mass in a calibrated cylinder per USP <616>. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by sulfuric acid treatment and final weighing of non-volatile residue as sulfate ash. |
Technical Specifications of 2-Bromo-5-chlorophenylacetic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Bromo-5-chlorophenylacetic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Bromo-5-chlorophenylacetic acid
Safety Information of 2-Bromo-5-chlorophenylacetic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Bromo-5-chlorophenylacetic acid
Industrial 2-Bromo-5-chlorophenylacetic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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