2-Chloro-5-fluorobenzyl bromide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 81778-09-8 |
| Product name | 2-Chloro-5-fluorobenzyl bromide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-5-fluorobenzyl bromide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-5-fluorobenzyl bromide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-5-fluorobenzyl bromide
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing fluorinated chlorobenzoylamide herbicides and insecticides | Used to construct the benzoylamide structure via nucleophilic substitution coupling with amines |
| Pharmaceuticals | Aromatic intermediate for synthesizing anticancer, anti-inflammatory, or central nervous system drugs | Acts as an electrophile in Suzuki coupling, Ullmann coupling, or Buchwald–Hartwig amination reactions |
| Dyes & Pigments | Precursor for synthesizing fluorinated heterocyclic dyes | Applied in the arylation step to build fluorinated benzo[d]thiazole or benzimidazole chromophores |
| Organic Synthesis | General fluorochloroarylating reagent | Introduces the 2-chloro-5-fluorophenyl group via transition-metal-catalyzed cross-coupling or nucleophilic aromatic substitution |
Manufacturing Quality Control of 2-Chloro-5-fluorobenzyl bromide
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities using reversed-phase C18 column and gradient elution with UV absorbance at 220 nm. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Headspace GC-FID analysis to quantify volatile organic solvents (e.g., methanol, acetone, dichloromethane) based on calibrated external standards. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated coulometrically reacts with water; endpoint detected by biamperometric method. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution and phenolphthalein indicator. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Multi-element quantitative analysis after acid digestion, measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Content | Potentiometric Titration with AgNO3 | Titration with silver nitrate using a silver indicator electrode; endpoint determined from inflection in potential vs. volume curve. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | Sample ignited at 700-800 C after sulfuric acid treatment; residue weighed as inorganic sulfate ash. |
| Melting Point | Capillary Melting Point Determination | Thermal transition observed visually or automatically as the temperature range over which solid transforms to liquid. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity if applicable. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard white background under controlled lighting. |
| Bulk Density | Graduated Cylinder Method | Mass of material divided by its untapped volume in a calibrated cylinder, reported in g/mL. |
Technical Specifications of 2-Chloro-5-fluorobenzyl bromide
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% (GC) |
| Total Impurities | <=1.5% (GC) |
| Single Impurity | <=0.5% (GC) |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.545–1.555 |
| Relative Density (20°C/25°C) | 1.58–1.62 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-5-fluorobenzyl bromide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-5-fluorobenzyl bromide
Safety Information of 2-Chloro-5-fluorobenzyl bromide
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-Chloro-5-fluorobenzyl bromide
Industrial 2-Chloro-5-fluorobenzyl bromide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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