2-Fluoro-5-nitrophenylboronic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 819849-20-2 |
| Product name | 2-Fluoro-5-nitrophenylboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Fluoro-5-nitrophenylboronic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Fluoro-5-nitrophenylboronic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Fluoro-5-nitrophenylboronic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antitumor, antiviral, or anti-inflammatory drugs | Used in Suzuki-Miyaura coupling to construct aryl–aryl bonds |
| Pesticides | Active ingredient synthesis for novel fluorinated aromatic pesticides | Applied in palladium-catalyzed cross-coupling to introduce fluoronitrophenyl groups |
| Materials Science | Preparation of organic optoelectronic materials (e.g., OLED emissive layers or electron-transport materials) | Employed in boronic acid-mediated coupling reactions to build π-conjugated systems |
| Chemical R&D | Multifunctional synthon for constructing libraries of complex aromatic compounds | Served as a key intermediate in multistep organic synthesis for C–C bond formation |
Manufacturing Quality Control of 2-Fluoro-5-nitrophenylboronic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, THF, toluene) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-free reagent; measures water via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, using isotopic detection with high sensitivity and low detection limits. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with suppressed conductivity detection; quantifies chloride relative to calibration standards. |
| Residue on Ignition | Gravimetric Analysis | Ignition of sample at 700-800 C to ash organic material, followed by weighing of inorganic residue as percentage of original mass. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of color and physical state (crystalline powder) against standard reference under controlled white light and specified viewing conditions. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined saturated aqueous suspension (e.g., 1% w/v) using calibrated pH electrode per USP <791>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering principles to determine D10, D50, D90 values per ISO 13320. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light through a solution in specified solvent and concentration, reported as degrees per dm*g/mL. |
Technical Specifications of 2-Fluoro-5-nitrophenylboronic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Conforms to reference standard |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Fluoro-5-nitrophenylboronic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Fluoro-5-nitrophenylboronic acid
Safety Information of 2-Fluoro-5-nitrophenylboronic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Fluoro-5-nitrophenylboronic acid
Industrial 2-Fluoro-5-nitrophenylboronic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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