China Factory Direct
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| CAS number | 82121-06-0 |
| Product name | 7-BROMO-4-HYDROXYQUINOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Structural building blocks for synthesizing antimalarial, antibacterial, and anticancer agents | Used as a key intermediate in coupling reactions (e.g., Suzuki, Heck) or nucleophilic substitution reactions to construct quinoline-based drug scaffolds |
| Organic Synthesis | Preparation of functionalized quinoline derivatives and ligands | Employed as a ligand precursor in metal-catalyzed reactions; the bromine atom undergoes selective transformation to introduce aryl, alkyl, or heteroatom substituents |
| Materials Science | Development of fluorescent probes and organic optoelectronic materials | Hydroxyl group modified via O-alkylation or N-alkylation, followed by further functionalization at the bromine site to tune luminescent properties and charge-transport characteristics |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~315 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., unreacted 4-hydroxyquinoline, bromination by-products) relative to main peak using gradient elution. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., DMF, chloroform, methanol) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element determination after acid digestion; quantification via emission intensity at characteristic wavelengths for Pb, Cd, Hg, As, Cr. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anion on an anion-exchange column with suppressed conductivity detection and external calibration. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-750 C followed by sulfuric acid treatment and final weighing of non-volatile residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as bulk phase change from solid to liquid, reported as onset and clear point range. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration against established reference standards. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying | Mass loss measured after drying under controlled temperature and vacuum/air flow; reflects volatile content including moisture and solvents. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity vs. angle to determine volume-based particle size distribution in dispersed dry or wet samples. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution at specified concentration, path length, and wavelength (e.g., 589 nm). |
| Test Item | Specification |
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| Appearance | Brown solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 172–176 °C |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm (as Pb) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.