PICOLINIC ACID N-OXIDE Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 824-40-8 |
| Product name | PICOLINIC ACID N-OXIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for PICOLINIC ACID N-OXIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk PICOLINIC ACID N-OXIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of PICOLINIC ACID N-OXIDE
| Industry | Application | Process |
|---|---|---|
| Pesticide Manufacturing | Serves as a key intermediate in the synthesis of sulfonylurea herbicides, such as nicosulfuron | Cyclization with isocyanates or isothiocyanates to prepare triazolopyrimidine sulfonamide herbicides |
| Pharmaceutical R&D | Used as a nitrogen-containing heterocyclic structural modification reagent for constructing N-oxidized pyridine pharmacophores | Participates in late-stage functionalization of drug molecules via coordination catalysis, oxidative addition, or as a hydrogen-bond acceptor to modulate pharmacokinetic properties |
| Organic Synthesis | Acts as a selective oxidation catalyst ligand or N-oxidized directing group to enhance regioselectivity in C–H bond activation | Enables ortho-C–H bond arylation or acetoxylation through N→M coordination in transition-metal (e.g., Pd, Ru) catalytic systems |
Manufacturing Quality Control of PICOLINIC ACID N-OXIDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Picolinic Acid N-Oxide Content) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against a certified reference standard. |
| Water Content | Karl Fischer Titration | Electrochemical titration where iodine reacts stoichiometrically with water in a methanol-based solvent system; endpoint detected potentiometrically. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents by gas chromatography with flame ionization detection using calibrated external standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection via inductively coupled plasma mass spectrometry after acid digestion; provides sub-ppt sensitivity and isotopic resolution. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with suppressed conductivity detection; quantified using chloride calibration standards. |
| Sulfate Impurity | Ion Chromatography | Same principle as chloride analysis, using sulfate-specific calibration and optimized eluent conditions for accurate quantification. |
| Related Substances | HPLC-DAD | Identification and quantification of structurally related impurities (e.g., picolinic acid, N-oxide degradation products) using diode array detection and retention time matching. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Direct measurement using a calibrated glass electrode in a 1% w/v aqueous solution at 25 C. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range over which solid-to-liquid phase change occurs under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled white light and specified viewing conditions. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying a sample at 105 C for 2 hours under vacuum or forced-air conditions, expressed as weight percent. |
| Residue on Ignition | Sulfated Ash Gravimetry | Weight of non-volatile inorganic residue remaining after high-temperature (700–800 C) incineration following sulfuric acid treatment. |
Technical Specifications of PICOLINIC ACID N-OXIDE
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 72-76°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of PICOLINIC ACID N-OXIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of PICOLINIC ACID N-OXIDE
Packaging of PICOLINIC ACID N-OXIDE
Industrial PICOLINIC ACID N-OXIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply