Fmoc-L-4-Iodophenylalanine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 82565-68-2 |
| Product name | Fmoc-L-4-Iodophenylalanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fmoc-L-4-Iodophenylalanine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-L-4-Iodophenylalanine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-L-4-Iodophenylalanine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Raw material for solid-phase peptide synthesis (SPPS) | Coupled with standard Fmoc-amino acids to incorporate L-4-iodophenylalanine residues |
| Chemical Synthesis | Intermediate for palladium-catalyzed cross-coupling reactions | Subjected to Sonogashira or Suzuki coupling, leveraging the high reactivity of the aryl iodide moiety |
| Biochemistry | Building block for constructing peptide libraries containing non-canonical amino acids | Employed in site-directed mutagenesis or non-canonical amino acid incorporation to investigate structure–activity relationships |
| Chemical Synthesis | Precursor for radiolabeled drugs or probes incorporating radioactive iodine | Functionalized via isotopic exchange or derivatization at the iodine substitution site |
Manufacturing Quality Control of Fmoc-L-4-Iodophenylalanine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 260-280 nm. |
| Identity | FTIR Spectroscopy | Verification by matching characteristic functional group absorption bands (e.g., amide I/II, aromatic C-H, C-I stretch) to a reference spectrum. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; L-isomer content determined by relative peak area versus racemic or D-isomer reference. |
| Residual Solvents | GC-FID | Qualitative and quantitative analysis of volatile organic solvents (e.g., DMF, DCM, MeOH) using flame ionization detection after headspace or direct injection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine/methanol buffer system. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, based on element-specific atomic emission intensities. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of Pd catalyst residues using mass spectrometric detection following microwave-assisted acid digestion. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation at 589 nm using a polarimeter; confirms chiral integrity and batch-to-batch consistency. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering pattern to derive D10, D50, D90 values. |
| pH (1% w/v aqueous suspension) | pH Meter | Measurement of hydrogen ion activity in a standardized aqueous suspension using calibrated glass electrode. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic mesophilic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial guidelines. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., deiodinated analog, diketopiperazine, Fmoc-Gly-OH) using gradient reversed-phase chromatography. |
Technical Specifications of Fmoc-L-4-Iodophenylalanine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% (by LC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -11.0 to -9.0° (c=1, in DMF) |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fmoc-L-4-Iodophenylalanine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-L-4-Iodophenylalanine
Packaging of Fmoc-L-4-Iodophenylalanine
Industrial Fmoc-L-4-Iodophenylalanine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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