1,2,3,4-Tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 82586-62-7 |
| Product name | 1,2,3,4-Tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 82586-62-7
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 82586-62-7 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 82586-62-7
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing dopamine receptor agonists or antagonists | Used as a chiral intermediate in organic synthesis to construct isoquinoline-based drug scaffolds |
| Chemical Research | Chiral compound studies and asymmetric synthesis | Applied in investigations of chiral catalytic reactions or as an optically active reference standard |
| Pharmaceutical Manufacturing | Raw material for potential neuroscience drug development | Derivatized to produce biologically active candidate drug molecules |
Manufacturing Quality Control of 82586-62-7
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~280 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation and quantification of (S)- and (R)-enantiomers on a chiral stationary phase, with UV detection to calculate enantiomeric excess (ee). |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine–methanol–sulfur dioxide medium. |
| Heavy Metals (as Pb) | ICP-MS | Multi-element trace metal quantification after acid digestion, using isotopic dilution or external calibration for metals including Pb, Cd, Hg, and As. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions in aqueous solution, quantified against chloride standard calibration. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Detection and quantification of structurally related impurities (e.g., des-methyl, oxidation, hydrolysis products) under stressed conditions (acid, base, heat, light, peroxide). |
| Loss on Drying (LOD) | Gravimetric Thermogravimetry | Mass loss measured after drying at 105 °C under vacuum or nitrogen until constant weight, reflecting volatile content including residual solvents and moisture. |
| pH (1% w/v aqueous suspension) | Potentiometric pH Measurement | Electrochemical measurement of hydrogen ion activity in a saturated aqueous suspension using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to determine volumetric particle size distribution in dispersed solid sample. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus, P. aeruginosa, C. albicans) per Ph. Eur./USP microbiological test guidelines. |
Technical Specifications of 82586-62-7
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–219 °C |
| Optical Rotation | +15.0 to +17.0 ° (c=1, in 1M HCl) |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 82586-62-7
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 82586-62-7
Industrial 82586-62-7 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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