China Factory Direct
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| CAS number | 82717-96-2 |
| Product name | N-[(S)-(+)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of angiotensin-converting enzyme (ACE) inhibitor intermediates | Used as a key chiral intermediate in the synthesis of antihypertensive drugs, such as ramipril, where the target molecular structure is constructed via condensation and hydrolysis steps |
| Test Item | Common Analytical Method | Method Description |
|---|---|---|
| Chemical Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyze hydrogen and carbon atom chemical shifts via ¹H-NMR and ¹³C-NMR to confirm molecular structure and stereochemistry. |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase chromatographic column and UV detector (e.g., 210–220 nm) to quantify the main component and detect related substance impurities. |
| Related Substances/Impurity Detection | HPLC (Gradient Elution) | Separate potential process impurities or degradation products using a gradient elution program, and assess impurity content based on relative retention time and peak area. |
| Enantiomeric Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use a chiral stationary phase column to separate and quantify diastereomers or enantiomer impurities to ensure optical purity. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Loss on Drying Method | Determine mass loss of the sample at a specified temperature (e.g., 105°C) under constant weight to evaluate moisture and volatile matter content. |
| Residual Solvents | Gas Chromatography (GC), Headspace Sampling | Quantify residual organic solvents (e.g., ethanol, ethyl acetate) according to ICH Q3C using a capillary column and FID detector. |
| Melting Point Determination | Capillary Melting Point Apparatus | Determine the melting point range as a physical constant for preliminary identification and purity assessment. |
| Specific Rotation | Polarimeter | Measure optical rotation at a specified wavelength (usually 589 nm, sodium D line) and concentration to verify the configuration and purity of chiral centers. |
| pH Value (in Solution) | pH Meter | Dissolve the sample into an aqueous solution at a certain concentration and measure pH to assess its acidity, basicity, and stability. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Determine residues of lead, arsenic, cadmium, mercury, etc. after digestion according to pharmacopoeia methods to ensure compliance with safety limits. |
| Ignition Residue | Muffle Furnace Ashing Method | Weigh the residue after high-temperature calcination (e.g., 600–800°C) to assess inorganic salt or metal catalyst residues. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C to 132°C |
| Optical Rotation | -24.0° to -26.0° (c=1, in DMF) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.