China Factory Direct
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| CAS number | 828-51-3 |
| Product name | 1-Adamantanecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical Intermediates | Used as organic synthesis intermediates in the production of antiviral, anticancer, and other therapeutic agents |
| Chemical Synthesis | Organic Synthesis Reagent | Applied in esterification, amidation, and other organic reactions as a carboxylic acid derivative |
| Materials Science | Functional Material Preparation | Applied in the preparation of polymeric or composite materials with specialized properties |
| Research | Analytical Reagent | Used as a reference standard or reaction reagent in laboratory analysis and research |
| Pesticides | Pesticide Synthesis Intermediate | Applied in synthetic routes for certain pesticides or plant growth regulators |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection and Physical Description | Observe the sample's color, state (typically a white crystalline powder), odor, and solubility, which should meet pharmacopoeia or internal quality control standards (e.g., white to off-white crystals, slightly soluble in water, easily soluble in ethanol and ether). |
| Melting Point | Melting Point Apparatus (Capillary Method) | According to General Chapter 0612 of the Chinese Pharmacopoeia, determine the melting point range (literature value approximately 265–268°C), and assess purity. A wide melting range indicates the presence of impurities. |
| Content Determination (Purity) | High-Performance Liquid Chromatography (HPLC) | Use a C18 chromatographic column, with a mobile phase of methanol-water or acetonitrile-water (with 0.1% formic acid), detected by a UV detector (UV 210–220 nm). Calculate the main component content using external standard method or internal standard method, typically requiring ≥98.0%. |
| Water Content | Karl Fischer Titration | Determine trace moisture using volumetric or coulometric methods, controlling water content within ≤0.5%, to avoid hydrolysis or affect stability. |
| Residual Solvents | Gas Chromatography (GC) | Use DB-624 or HP-INNOWAX columns with headspace injection to detect residual organic solvents such as ethanol, acetone, and ether, meeting ICH Q3C standard limits. |
| Heavy Metals | Atomic Absorption Spectrometry (AAS) or ICP-MS | After sample digestion, determine the content of heavy metals such as lead, cadmium, mercury, and arsenic, meeting pharmacopoeia requirements (e.g., Pb ≤ 5 ppm). |
| Related Substances (Impurity Profile) | HPLC (Gradient Elution) | Use a gradient elution program to separate and quantify process impurities and degradation products (e.g., adamantanol, unreacted raw materials), controlling individual impurities ≤0.5% and total impurities ≤1.0%. |
| Chlorides, Sulfates | Colorimetric Method (Pharmacopoeia General Method) | After ashing or dissolving the sample, compare with standard sodium chloride or potassium sulfate solutions by colorimetry, controlling chlorides ≤0.01% and sulfates ≤0.02% (according to USP/EP general chapters). |
| pH Value (Aqueous Solution) | pH Meter Measurement | Prepare a saturated aqueous solution (or specified concentration) of the sample, and measure its pH using a calibrated pH meter. It is usually weakly acidic (pH 4–6), reflecting the integrity of acidic functional groups. |
| Particle Size Distribution (if powder) | Laser Diffraction or Microscopy | For raw materials used in formulations requiring flowability, determine the particle size distribution (e.g., D50), ensuring it meets subsequent process requirements (e.g., tablet compression, mixing homogeneity). |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare characteristic absorption peaks with standard spectra (e.g., carboxyl group C=O stretching vibration around 1710 cm⁻¹, C–H bending vibration around 1380 cm⁻¹), confirming molecular structure accuracy. |
| Polymorphic Analysis | X-ray Powder Diffraction (XRPD) | Used to confirm the crystalline form is consistent, avoiding differences in polymorphism that may affect solubility and stability (especially important in formulation development). |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 215-218°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Acid Value (mg KOH/g) | 185-195 mg KOH/g |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.