China Factory Direct
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| CAS number | 82834-12-6 |
| Product name | N-[(S)-1-Carbethoxy-1-butyl]-(S)-alanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceuticals | Intermediate in the synthesis of peptide-based drugs, used to construct specific chiral amino acid structures | Amidation reaction between (S)-alanine derivative and ethoxycarbonyl-1-butyl chloride via chiral synthesis pathway |
| Biochemistry | Protected amino acid component in peptide synthesis, improving product purity and yield | Key monomer in solid-phase or solution-phase peptide synthesis, introduced using Fmoc or Boc protection strategy |
| Advanced Materials | Preparation of functional polymeric materials with defined stereochemical architecture | Incorporated as a chiral monomer in copolymerization or crosslinking reactions |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white to off-white powder), and presence of visible foreign particles. |
| Identification | Infrared Spectroscopy (IR) | Compare the sample spectrum with the reference standard spectrum to confirm consistency of functional groups and molecular structure. |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ¹³C-NMR) | Analyze hydrogen and carbon spectra to determine structural characteristics and confirm the chemical structure of the target compound. | |
| Mass Spectrometry (MS) | Determine the molecular ion peak to verify whether the measured molecular weight matches the theoretical value (e.g., ESI-MS or EI-MS). | |
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with UV detection (e.g., 210 nm or 254 nm), employing gradient or isocratic elution; calculate main peak purity using external standard method or area normalization. |
| Chiral Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Utilize chiral stationary phase columns (e.g., Chiralpak AD-H, AS-H) to separate enantiomers and determine enantiomeric excess (ee value) of the (S,S) configuration. |
| Moisture Content | Karl Fischer Titration | Accurately measure water content in the sample, suitable for quality control of active pharmaceutical ingredients. |
| Residual Solvents | Gas Chromatography (GC) | Test for residual organic solvents from manufacturing processes according to ICH guidelines (e.g., methanol, ethanol, ethyl acetate, dichloromethane). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate and detect process impurities and degradation products using gradient elution; typically requires detection sensitivity of 0.1% or lower. |
| Melting Point | Melting Point Determination by Melting Point Apparatus | Determine the melting temperature range as an initial assessment of purity and batch consistency. |
| Specific Rotation | Polarimeter Method | Measure specific rotation under specified wavelength (e.g., sodium D line at 589 nm) and temperature to evaluate chiral purity and batch consistency. |
| Ash/Residue on Ignition | Residue on Ignition Method | Ignite sample at high temperature and weigh the remaining residue to assess inorganic impurity levels. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detect trace heavy metals such as lead, cadmium, mercury, and arsenic, complying with pharmacopoeial or ICH Q3D requirements. |
| Microbial Limits | Microbial Limit Test | Includes total aerobic microbial count, mold and yeast count, and control organism testing (e.g., Escherichia coli); applicable to non-sterile raw materials. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 62–66°C |
| Optical Rotation | +2.8 to +3.4° (c=1, in CHCl3) |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.