China Factory Direct
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| CAS number | 82911-69-1 |
| Product name | N-(9-Fluorenylmethoxycarbonyloxy)succinimide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for drug synthesis | Used as an amino-protecting reagent in peptide or protein synthesis |
| Chemical Synthesis | Organic synthesis reagent | Applied to introduce the fluorenylmethyloxycarbonyl (Fmoc) protecting group, particularly for amine protection |
| Biotechnology | Protein labeling and modification | Applied to label or modify primary amine groups in proteins to facilitate subsequent detection or purification |
| Materials Science | Functional material preparation | Used in synthesizing functional polymers or resins as a structural unit or crosslinker |
| Analytical Chemistry | Derivatization reagent | Applied in chromatographic analysis to derivatize amines or amino acids, enhancing detection sensitivity |
| Immunology | Antigen–antibody conjugate preparation | Used to form chemical crosslinks in antigen–antibody complexes |
| Nanotechnology | Nanocarrier functionalization | Applied to modify nanoparticle surfaces, conferring specific chemical reactivity or targeting capability |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and state (usually white to off-white crystalline powder) to determine the presence of foreign matter or discoloration. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with acetonitrile-water or methanol-water as the mobile phase, and a UV detector (e.g., 265 nm) to measure the main peak area for purity calculation. |
| Content (Active Ingredient Quantification) | HPLC External Standard Method or Internal Standard Method | Determine the content of FMOC-OSu by comparing the peak area with that of the standard, typically requiring ≥98.0%. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at specified temperature (e.g., 60–80°C) under vacuum until constant weight is achieved, and calculate the percentage of mass loss to assess moisture and volatile impurities. |
| Melting Point | Melting Point Apparatus | Determine the melting point range of the sample (FMOC-OSu typical melting point ~203–207°C), used to evaluate purity and crystallinity consistency. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection GC to detect residual organic solvents (e.g., dichloromethane, acetonitrile) from the synthesis process. |
| pH Value (Solution) | pH Meter Measurement | Dissolve the sample in a certain concentration water/organic mixed solution and measure its pH, indirectly reflecting the presence of acidic or basic impurities. |
| UV-Visible Absorption Spectrum | UV-Visible Spectrophotometry (UV-Vis) | Measure absorbance at specific wavelengths (e.g., 265 nm, 290 nm) for qualitative identification and auxiliary purity assessment. |
| Infrared Spectrum (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Confirm molecular structure through characteristic functional group absorption peaks (e.g., N-hydroxysuccinimide carbonyl ~1740 cm⁻¹, carbonate ester C=O ~1800 cm⁻¹). |
| Nuclear Magnetic Resonance Hydrogen Spectrum (¹H NMR) | Nuclear Magnetic Resonance Spectroscopy | Determine in deuterated solvent (e.g., DMSO-d₆) to confirm molecular structural integrity and detect obvious impurity signals. |
| Water Content | Karl Fischer Titration Method | Specifically determine the water content in the sample, especially important for compounds prone to hydrolysis. |
| Related Substances (Impurities) | HPLC Gradient Elution Method | Separate and detect potential degradation products or synthetic by-products (e.g., FMOC-OH, NHS) using gradient elution programs. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 168–172°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.