4-Aminoantipyrine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 83-07-8 |
| Product name | 4-Aminoantipyrine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Aminoantipyrine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Aminoantipyrine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Aminoantipyrine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Drug Synthesis | Used in the synthesis of certain antipyretic and analgesic drugs, such as antipyrine derivatives |
| Analytical Chemistry | Analytical Reagent | Used to detect trace phenolic compounds—e.g., phenol—in water via colorimetric determination, forming a red antipyrine dye upon reaction with phenols |
| Dye Industry | Intermediate | Applied as an intermediate in the synthesis of certain dyes and pigments |
| Research Institutions | Research Reagent | Used in laboratory research, particularly as a reference standard or control reagent in analytical chemistry |
| Environmental Monitoring | Water Quality Testing | Applied in environmental water quality monitoring, especially for quantitative analysis of phenolic pollutants in industrial wastewater |
Manufacturing Quality Control of 4-Aminoantipyrine
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Characteristics | Visual inspection, Melting point determination | Observe the sample's color and crystalline state; determine the melting point range (literature value approximately 124–127°C), to assess purity and whether it has been exposed to moisture or degraded. |
| Content Determination | High-performance liquid chromatography (HPLC) | Using a C18 chromatographic column, with methanol-water or acetonitrile-phosphate buffer as the mobile phase, UV detector (254 nm or 280 nm) for detection, quantification via external standard or internal standard method. Accurate and suitable for API content determination. |
| Content Determination | UV-Visible Spectrophotometry (UV-Vis) | Determine absorbance at specific wavelengths (e.g., 280–290 nm), quantify using a standard curve. Simple operation, but susceptible to interference from impurities; suitable for rapid screening or samples of high purity. |
| Impurity Detection | High-performance liquid chromatography (HPLC) | Using gradient or isocratic elution to detect potential degradation products (e.g., oxidation products, unreacted raw materials, azo impurities), calculate impurity content by comparison with reference standards, ensuring compliance with pharmacopoeia impurity limits. |
| Moisture Content | Karl Fischer Titration | Quantitatively determine trace moisture using an iodine-sulfur dioxide-pyridine-methanol system, ensuring drying conditions meet storage requirements (typically ≤0.5%). |
| Solvent Residue | Gas Chromatography (GC) | Detect residual organic solvents (e.g., methanol, ethanol, ethyl acetate) used in production, using headspace or direct injection, with FID detector, meeting ICH Q3C solvent residue limits. |
| Heavy Metal Detection | Atomic Absorption Spectrometry (AAS) or ICP-MS | Determine heavy metals such as lead, cadmium, mercury, and arsenic after sample digestion, ensuring compliance with pharmacopoeia limits (e.g., lead ≤10 ppm). |
| pH Value Determination | pH meter method | Determine pH by preparing a water solution (e.g., 1% w/v), assessing acidity or alkalinity to meet formulation process requirements (usually neutral or slightly acidic). |
| Solubility Determination | Shake Flask Method / Pharmacopoeia Solubility Test Method | Determine saturated solubility in different solvents (water, ethanol, acetone, etc.), guiding formulation design to ensure good dissolution performance in drug delivery media. |
| Particle Size Distribution (if applicable) | Laser Diffraction or Microscopy | For powdered APIs, measure particle size distribution, which affects dissolution rate and formulation uniformity, especially for inhalation or oral solid dosage forms. |
| Infrared Spectroscopy Identification | Fourier Transform Infrared Spectroscopy (FTIR) | Acquire the infrared absorption spectrum of the sample and compare it with the standard spectrum to confirm chemical structure consistency, used for qualitative identification. |
Technical Specifications of 4-Aminoantipyrine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% (HPLC) |
| Melting Point | 109.0–111.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Aminoantipyrine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Aminoantipyrine
Packaging of 4-Aminoantipyrine
Industrial 4-Aminoantipyrine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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