China Factory Direct
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| CAS number | 83-15-8 |
| Product name | 4-ACETAMIDOANTIPYRINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antipyretic and analgesic drugs | Prepared via acetylation; commonly employed in synthetic pathways for antipyrine-class drugs |
| Analytical Chemistry | Used as a colorimetric reagent for detecting phenolic compounds (e.g., phenol, p-cresol) | Undergoes coupling reactions with phenolic compounds under alkaline conditions to form colored complexes for spectrophotometric determination |
| Environmental Monitoring | Used for quantitative detection of phenolic pollutants in water quality analysis | Reacts with phenols in alkaline media to yield red or violet-red products; quantified by absorbance measurement |
| Biochemistry | Used as a substrate or reagent in enzymatic reactions, particularly in redox reaction studies | Employed in mechanistic studies of enzyme systems such as peroxidase for activity assays |
| Chemical Research | Used in coupling reactions and construction of intermediates in organic synthesis | Applied as an aromatic amine derivative in multistep syntheses for the design and development of novel compounds |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against a certified reference standard. |
| Appearance | Visual Inspection | Assessment of physical state and color by observation against standard white background under controlled lighting. |
| Melting Point | Capillary Melting Point Determination | Measurement of temperature range over which solid transitions to liquid using calibrated capillary apparatus. |
| Loss on Drying | Gravimetric (Oven Drying) | Determination of volatile content by weight loss after drying at 105 C for 2 hours under atmospheric pressure. |
| Residue on Ignition | Gravimetric (Sulfated Ash) | Measurement of non-volatile inorganic residue after ignition at 700-800 C following sulfuric acid treatment. |
| Heavy Metals (as Pb) | Colorimetric (Thiourea Method) | Qualitative/semi-quantitative detection via formation of colored complex with thiourea under acidic conditions. |
| Chloride Impurity | Argentometric Titration (Mohr Method) | Titration with standardized silver nitrate solution using potassium chromate indicator; endpoint signaled by brick-red precipitate. |
| Sulfate Impurity | Barium Sulfate Turbidimetry | Quantification based on turbidity generated by precipitation of barium sulfate in acidic medium. |
| Related Substances | HPLC-DAD | Separation and detection of structurally related impurities using gradient HPLC with diode-array detection and comparison to reference standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric determination of water based on iodine consumption in pyridine-methanol solvent system. |
| pH of Solution (1% w/v) | Potentiometric pH Measurement | Measurement of hydrogen ion activity in aqueous suspension using calibrated glass electrode pH meter. |
| Solubility in Ethanol | Visual Solubility Test | Qualitative assessment of complete dissolution in specified volume of ethanol at 20 C with gentle agitation. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 113.0–117.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.