China Factory Direct
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| CAS number | 83774-13-4 |
| Product name | 4-Chloro-6-isopropoxypyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides / Agrochemicals | Key intermediate for synthesizing pyrimidine-based herbicides (e.g., pyributicarb, bispyribac-sodium) | Condensed with aryl halides or other heterocyclic compounds via nucleophilic substitution or coupling reactions to construct the target herbicide molecular framework |
| Pharmaceutical R&D | Used to synthesize biologically active pyrimidine derivatives with potential application in anticancer, antiviral, or anti-inflammatory drug development | Serves as a heterocyclic building block in multistep organic synthesis, including modern catalytic reactions such as Suzuki coupling and Buchwald–Hartwig amination |
| Fine Chemicals | Functional organic intermediate for custom synthesis of high-value-added chemicals | Under inert atmosphere, undergoes selective functional group transformations—such as alkoxy exchange or chlorine atom substitution—to yield end products with specified performance attributes |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 245 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode array detection; relative retention times and UV spectra support structural assignment. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., isopropanol, acetone, dichloromethane) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using isotopic detection for high sensitivity and selectivity. |
| Chloride Ion Impurity | Ion Chromatography | Separation of anions on anion-exchange column with suppressed conductivity detection; chloride quantified against calibration standards. |
| Residue on Ignition | Gravimetric Analysis | Mass loss measured after heating sample at 700-800 C in a platinum crucible; residue weight reflects inorganic ash content. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range where solid transforms to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assessment under controlled white light against standard references for color, clarity, and presence of particulates or foreign matter. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity vs. angle to derive volume-weighted particle size distribution in dry or dispersed state. |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume after standardized tapping; indicates flowability and packing behavior for formulation use. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through solution; confirms chiral integrity and absence of racemization. |
| Test Item | Specification |
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| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | -15 to -10°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.