China Factory Direct
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| CAS number | 84-52-6 |
| Product name | CYTIDINE 3'-MONOPHOSPHATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Nucleotide-based drug intermediates for synthesizing antiviral agents (e.g., cytarabine derivatives) and anticancer drugs | Used as a building block in solid-phase or solution-phase synthesis; incorporated into oligonucleotide chains via phosphorylation, protection/deprotection, and related steps |
| Life Science Research | Biochemical reagent for RNA synthesis and modification studies, serving as substrate for enzymatic reactions or probe labeling | Acts as a substrate for kinases (e.g., nucleoside diphosphate kinase) or polymerases (e.g., T4 RNA ligase) in in vitro transcription or labeling reactions |
| Diagnostics | Modified nucleotide component in molecular diagnostic kits for nucleic acid amplification or hybridization assays | Employed as an auxiliary substrate in isothermal amplification systems (e.g., RT-PCR, NASBA) to enhance specificity or signal sensitivity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies cytidine 3'-monophosphate by reversed-phase HPLC with UV detection at 280 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., cytidine, CMP isomers, hydrolysis products) using gradient HPLC-UV. |
| Water Content | Karl Fischer Titration | Determines trace water content via coulometric or volumetric titration with iodine-based reagent, based on stoichiometric water-iodine reaction. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by ignition at 700-800 C followed by weighing of residual non-volatile matter. |
| Heavy Metals | ICP-OES | Quantifies Pb, Cd, Hg, As, and other heavy metals after acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Chloride | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection. |
| pH (1% aqueous solution) | Potentiometric Titration | Measures hydrogen ion activity using calibrated pH electrode in a 1% w/v aqueous solution at 25 C. |
| Optical Rotation | [alpha]D | Determines specific optical rotation using sodium D-line light (589 nm) in aqueous solution to confirm chiral integrity. |
| Loss on Drying | Thermogravimetric Analysis | Measures weight loss after drying at 105 C under vacuum or nitrogen, indicating volatile solvents and moisture. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms, yeasts, and molds by filtration, membrane transfer to selective media, and colony enumeration. |
| Endotoxins | LAL Assay | Quantifies bacterial endotoxins using Limulus amebocyte lysate reagent, based on enzymatic clotting cascade triggered by endotoxin. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry powder form using Mie scattering theory applied to laser diffraction patterns. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15.0° to -19.0° (c=1, H2O) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.