Fmoc-N-methyl-L-valine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 84000-11-3 |
| Product name | Fmoc-N-methyl-L-valine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for Fmoc-N-methyl-L-valine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-N-methyl-L-valine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-N-methyl-L-valine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a non-natural amino acid in peptide synthesis to construct peptide therapeutics with defined conformation or enhanced metabolic stability | Employed as an Fmoc-protected N-methylated amino acid monomer in solid-phase peptide synthesis (SPPS), incorporated into the peptide chain under standard coupling conditions (e.g., HBTU/DIPEA) |
| Biochemical Research | Used to investigate the effects of N-methylation on peptide secondary structure, membrane permeability, and protease resistance | Incorporated as a structural modification unit into target sequences during laboratory-scale peptide synthesis, followed by deprotection and purification |
| Peptide Synthesis Reagent Manufacturing | Supplied as a high-purity Fmoc-protected amino acid raw material to peptide synthesis service providers and pharmaceutical companies | Prepared via chemical synthesis, purified by recrystallization or chromatography, and stored and distributed as a lyophilized powder |
Manufacturing Quality Control of Fmoc-N-methyl-L-valine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 268 nm, comparing peak area to certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., Fmoc-Val, N-methyl-Val, di-Fmoc derivatives) via gradient HPLC-UV. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, DCM, MeOH) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration based on iodine-sulfur dioxide reaction in pyridine-free reagent. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation using sodium D-line light source to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Quantifies metals (e.g., Pb, Cd, Ni, Fe) after acid digestion by plasma emission spectroscopy at element-specific wavelengths. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| pH (1% w/v aqueous suspension) | pH Meter | Measures hydrogen ion activity in a standardized suspension using calibrated pH electrode and buffer reference. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution by measuring angular scattering pattern of laser beam through dispersed sample. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) using selective culture media and incubation. |
Technical Specifications of Fmoc-N-methyl-L-valine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -71.0 to -65.0 deg (c=1, in DMF) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of Fmoc-N-methyl-L-valine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-N-methyl-L-valine
Packaging of Fmoc-N-methyl-L-valine
Industrial Fmoc-N-methyl-L-valine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply