China Factory Direct
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| CAS number | 84162-86-7 |
| Product name | 1-(2',4'-Difluorophenyl)-1-(4-piperidinyl) methanone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing anti-inflammatory drugs | Used in organic synthesis reactions |
| Pesticides | Intermediate for insecticides or herbicides | Applied in acylation reactions |
| Chemical raw materials | Starting material for synthesizing other organic compounds | Employed in catalytic hydrogenation or other organic transformation processes |
| Test Item | Common Analytical Methods | Method Summary |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Using a reversed-phase C18 column with an acetonitrile-buffer mobile phase for gradient elution, and a UV detector (e.g., 254 nm) for quantification of the main component. The method has strong specificity and good repeatability, and is a core method for quality control. |
| Related Substances/Impurity Analysis | HPLC (Gradient Elution) | Optimize the gradient program to separate the main peak from potential impurities (such as synthetic intermediates and degradation products), using area normalization or external standard methods for quantification, to evaluate purity and impurity profile. |
| Residual Solvents | Gas Chromatography (GC-FID or GC-MS) | Based on ICH Q3C guidelines, using headspace or direct injection, with DB-624 or similar capillary columns for separation, and FID detection for common organic solvent residues (such as methanol, ethyl acetate, DMF, etc.). |
| Dry Loss | Drying Method | Dry the sample at 105°C until constant weight, calculate the percentage of mass loss to assess the content of volatile substances (water, solvents). Applicable to solid dosage form APIs. |
| Ignition Residue | High-Temperature Ashing Method | After carbonization with sulfuric acid, the sample is incinerated in a muffle furnace at 700–800°C, and the remaining inorganic substance is weighed to control inorganic impurities or residual metal catalysts. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectrometry (AAS) | After microwave digestion of the sample, determine the content of elements such as lead, cadmium, mercury, and arsenic using ICP-MS or AAS, complying with ICH Q3D elemental impurity limits. |
| Moisture | Karl Fischer Titration (Volumetric or Coulometric Method) | Utilize the quantitative reaction between iodine and sulfur dioxide in a pyridine/imidazole system with water to accurately determine trace moisture in the sample, which significantly affects stability. |
| Melting Point | Capillary Melting Point Method | Determine the temperature range from initial melting to complete melting of a solid sample, used as a physical constant for identification and preliminary purity assessment. |
| Specific Rotation (if chiral) | Polarimeter Method | If the molecule contains a chiral center, measure its specific rotation ([α]D) for identification and optical purity control. This compound does not contain a chiral center, so this test may be omitted. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), Mass Spectrometry (MS) | Use NMR (¹H, ¹³C, 19F) to confirm the molecular framework; use IR to verify functional groups (such as carbonyl, aromatic rings); use MS (ESI or EI) to determine molecular weight and fragment characteristics, comprehensively confirming the chemical structure. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.