China Factory Direct
|
|
| CAS number | 84194-30-9 |
| Product name | 2-Chloro-5-fluorobenzaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the anticancer drug gefitinib | Constructs the quinazoline core via multistep organic synthesis, involving condensation and cyclization of 2-chloro-5-fluorobenzaldehyde with malononitrile |
| Agrochemicals | Structural building block for synthesizing novel fluorinated benzamide fungicides (e.g., fluopyram analogues) | Serves as a starting material in nucleophilic addition, reductive amination, and amidation reactions to introduce the chloro-fluoro-substituted benzaldehyde side chain |
| Materials Science | Building block for fluorinated liquid crystal monomers and organic light-emitting diode (OLED) materials | Introduces alkenyl or aryl groups via Wittig reaction or Grignard addition, followed by oxidation, halogenation, and other modifications to tune molecular polarity and thermal stability |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of mechanical impurities under natural light or standard illumination. |
| Purity (Content) | High-Performance Liquid Chromatography (HPLC) | Utilize a reversed-phase C18 column with UV detection (e.g., 254 nm), quantifying the main component via external standard method or normalization method. |
| Gas Chromatography (GC) | Applicable to samples with good volatility; use FID detector, identify components by retention time and quantify by peak area. | |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H-NMR and ¹³C-NMR to confirm compound structure by comparing characteristic peaks with reference spectra. |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Confirm functional groups (e.g., aldehyde C=O, C–Cl, C–F) by analyzing infrared absorption spectra. | |
| Mass Spectrometry (MS) | Employ EI or ESI ionization to obtain molecular ion peaks ([M]+), assisting in structural identification and molecular weight confirmation. | |
| Moisture Content | Karl Fischer Titration | Determine water content precisely using coulometric titration based on the reaction between iodine, sulfur dioxide, and water in methanol. |
| Residual Solvents | Gas Chromatography (GC) | Test for potentially residual organic solvents (e.g., methanol, ethanol, dichloromethane) according to ICH Q3C guidelines. |
| Melting Point | Melting Point Apparatus Method | Determine initial and final melting temperatures using automatic or capillary melting point apparatus to assess purity and consistency. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, measure residual levels of heavy metals such as lead, cadmium, mercury, and arsenic to meet pharmacopeial or safety standards. |
| Chlorine/Fluorine Content Verification | Elemental Analysis (CHNS/O Analysis) | Determine actual contents of C, H, N, S, and halogens (combined with oxygen bomb combustion-ion chromatography if necessary) to verify composition. |
| Impurity Profiling | HPLC or GC-MS | Separate and identify process-related impurities and degradation products; commonly used for related substances testing to evaluate sample stability. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 42–46°C |
| Identification (NMR) | Conforms to reference standard |
| Identification (IR) | Conforms to reference standard |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.